The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells (Q41152946)

27 September 2017

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title

The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells (English)

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27 September 2017

D L Eizirik

1

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27 September 2017

M Flodström

series ordinal

2

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27 September 2017

A E Karlsen

series ordinal

3

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27 September 2017

N Welsh

series ordinal

4

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27 September 2017

publication date

1 August 1996

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27 September 2017

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27 September 2017

volume

39

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27 September 2017

issue

8

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27 September 2017

page(s)

875-890

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Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

27 September 2017

cites work

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene.

1 reference

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12 December 2020

Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Polygenic control of autoimmune diabetes in nonobese diabetic mice

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12 December 2020

Liposomal delivery of antioxidant enzymes protects against hydrogen peroxide- but not interleukin-1 beta-induced inhibition of glucose metabolism in rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cytokine signaling through nonreceptor protein tyrosine kinases

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The inducible form of nitric oxide synthase (iNOS) in insulin-producing cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nicotinamide inhibits IRF-1 mRNA induction and prevents IL-1 beta-induced nitric oxide synthase expression in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The inducible nitric oxide synthase gene, Nos2, maps to mouse chromosome 11

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin-dependent) diabetes mellitus?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide synthase structure and mechanism

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Biochemical and Molecular Actions of Interleukin-1 on Pancreatic β-Cells

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https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Repair of pancreatic beta-cells. A relevant phenomenon in early IDDM?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Three members of the nitric oxide synthase II gene family (NOS2A, NOS2B, and NOS2C) colocalize to human chromosome 17.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Tyrosine kinase involvement in IL-1 beta-induced expression of iNOS by beta-cells purified from islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The high-output nitric oxide pathway: role and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide donors decrease the function and survival of human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Transforming growth factor-beta inhibits the cytokine-mediated expression of the inducible nitric oxide synthase mRNA in human retinal pigment epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta induces the expression of an isoform of nitric oxide synthase in insulin-producing cells, which is similar to that observed in activated macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Regional localization of the gene coding for human brain nitric oxide synthase (NOS1) to 12q24.2-->24.31 by fluorescent in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Localization and characterization of interleukin-1 receptors in the islets of Langerhans from control and nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Insulin-dependent diabetes mellitus as a beta-cell targeted disease of immunoregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Dissociation between Interleukin-1β-Induced Expression of mRNA for Superoxide-Dismutase and Nitric Oxide Synthase in Insulin-Producing Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

On the expression of nitric oxide synthase by human macrophages. Why no NO?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Heat shock protein induction in rat pancreatic islets by recombinant human interleukin 1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta-induced nitric oxide synthase expression by rat pancreatic beta-cells: evidence for the involvement of nuclear factor kappa B in the signaling mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase. Activation by nuclear factor-kappa B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nicotinamide and dexamethasone inhibit interleukin-1-induced nitric oxide production by RINm5F cells without decreasing messenger ribonucleic acid expression for nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Molecular genetic analysis of the duplication of human inducible nitric oxide synthase (NOS2) sequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Influence of protease on inhibitory and stimulatory effects of interleukin 1 beta on beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Coinduction of nitric oxide synthase, argininosuccinate synthetase, and argininosuccinate lyase in lipopolysaccharide-treated rats. RNA blot, immunoblot, and immunohistochemical analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Tyrosine kinase inhibitors, genistein and herbimycin A, do not block interleukin-1 beta-induced activation of NF-kappa B in rat mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Secretory products of macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 induces rapid and transient expression of the c-fos proto-oncogene in isolated pancreatic islets and in purified beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase*

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Structural diversity in the 5'-untranslated region of cytokine-stimulated human inducible nitric oxide synthase mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Ceramide activates the stress-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

New insights into the regulation of inducible nitric oxide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 stimulates the expression of type I and type II interleukin-1 receptors in the rat insulinoma cell line Rinm5F; sequencing a rat type II interleukin-1 receptor cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Strain-Dependent Differences in Sensitivity of Rat -Cells to Interleukin 1 In Vitro and In Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Role of receptor binding and gene transcription for both the stimulatory and inhibitory effects of interleukin-1 in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1β Increases the Biosynthesis of the Heat Shock Protein hsp70 and Selectively Decreases the Biosynthesis of five Proteins in rat Pancreatic Islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Molecular cloning and characterization of human endothelial nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide activates cyclooxygenase enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11.2-q12

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Islet cell DNA is a target of inflammatory attack by nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

A role for tyrosine kinase activation in interleukin-1 beta induced nitric oxide production in the insulin producing cell line RINm-5F.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Promoter analysis of human inducible nitric oxide synthase gene associated with cardiovascular homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1β induces the expression of HSP70, heme oxygenase and Mn-SOD in FACS-purified rat islet β-cells, but not in α-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide: a physiologic messenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Coinduction of nitric oxide synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxide production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Arginine metabolism in wounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Studies on the molecular regulation of the inducible form of nitric oxide synthase (iNOS) in insulin-producing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Mapping of the Genes Encoding Human Inducible and Endothelial Nitric Oxide Synthase (NOS2 and NOS3) to the Pericentric Region of Chromosome 17 and to Chromosome 7, Respectively

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Succinic acid monomethyl ester protects rat pancreatic islet secretory potential against interleukin-1 beta (IL-1 beta) without affecting glutamate decarboxylase expression or nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Increased intracellular Ca2+ selectively suppresses IL-1-induced NO production by reducing iNOS mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Insulin-secreting beta-cells possess specific receptors for interleukin-1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The L-arginine-nitric oxide pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nicotinamide Decreases Nitric Oxide Production and Partially Protects Human Pancreatic Islets Against the Suppressive Effects of Combinations of Cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Induction of nitric oxide synthase mRNA expression. Suppression by exogenous nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

A natural interleukin 1 (IL-1) inhibitor counteracts the inhibitory effect of IL-1 on insulin production in cultured rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin‐1 ‐induced expression of nitric oxide synthase in insulin‐producing cells is preceded by c‐fos induction and depends on gene transcription and protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloning and characterization of inducible nitric oxide synthase from mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

An interleukin-1 receptor antagonist protein protects insulin-producing Beta cells against suppressive effects of interleukin-1?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Role of endothelium-derived nitric oxide in the regulation of blood pressure

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Functional characteristics of rat pancreatic islets maintained in culture after exposure to human interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-10 stimulates rat pancreatic islets in vitro, but fails to protect against interleukin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-gamma in murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide synthases: properties and catalytic mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cloning and expression of cytokine-inducible nitric oxide synthase cDNA from rat islets of Langerhans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Co-induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide: first in a new class of neurotransmitters

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Messenger RNA degradation in eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Recombinant human transforming growth factor beta does not inhibit the effects of interleukin-1 beta on pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Cytokine and free radicals as effector molecules in the destruction of pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide synthase: expression and expressional control of the three isoforms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Calmodulin is a subunit of nitric oxide synthase from macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Modulation of inducible nitric oxide synthase in RINm5F cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Natural resistance and nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Interleukin-1 beta induced activation of NF-kappa B in insulin producing RINm5F cells is prevented by the protease inhibitor N alpha-p-tosyl-L-lysine chloromethylketone

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Type 1 (insulin-dependent) diabetes mellitus and nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Nitric oxide limits transcriptional induction of nitric oxide synthase in CNS glial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Inducible nitric-oxide-synthase mRNA is transiently expressed and destroyed by a cycloheximide-sensitive process

1 reference

https://pubmed.ncbi.nlm.nih.gov/8858209

12 December 2020

Identifiers

DOI

10.1007/S001250050528

1 reference

27 September 2017

1 reference