Cbl: complex formation and functional implications (Q40844906)

24 September 2017

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title

Cbl: complex formation and functional implications (English)

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24 September 2017

Y C Liu

1

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24 September 2017

A Altman

series ordinal

2

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24 September 2017

publication date

1 June 1998

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24 September 2017

number of pages

9

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inferred from page(s)

published in

Cellular Signalling

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24 September 2017

volume

10

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24 September 2017

issue

6

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24 September 2017

page(s)

377-385

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v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

24 September 2017

cites work

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7 January 2021

The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein

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7 January 2021

The cbl oncogene: a novel substrate of protein tyrosine kinases

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7 January 2021

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Identification and preliminary characterization of a protein motif related to the zinc finger

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7 January 2021

Does this have a familiar RING?

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7 January 2021

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways

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7 January 2021

The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

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7 January 2021

Relationship of the human protooncogene CBL2 on 11q23 to the t(4;11), t(11;22), and t(11;14) breakpoints

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7 January 2021

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

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7 January 2021

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

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7 January 2021

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

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7 January 2021

Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

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7 January 2021

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

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7 January 2021

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

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7 January 2021

Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter

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7 January 2021

Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl

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7 January 2021

Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation

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7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

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7 January 2021

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase

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7 January 2021

Induction of CD38/NADase and its monoclonal antibody-induced tyrosine phosphorylation in human leukemia cell lines

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7 January 2021

Association of phosphatidylinositol 3-kinase with the proto-oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP-1 cells

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7 January 2021

Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors

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7 January 2021

Specific association of phosphatidylinositol 3-kinase with the protooncogene product Cbl in Fc gamma receptor signaling

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7 January 2021

Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells

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7 January 2021

Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages

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7 January 2021

Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase

1 reference

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7 January 2021

The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

1 reference

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7 January 2021

TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules

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7 January 2021

Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation

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7 January 2021

Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.

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7 January 2021

Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase

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7 January 2021

Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation

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7 January 2021

Coupling of the Proto-oncogene Product c-Cbl to the Epidermal Growth Factor Receptor

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7 January 2021

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

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7 January 2021

c-Cbl is inducibly tyrosine-phosphorylated by epidermal growth factor stimulation in fibroblasts, and constitutively tyrosine-phosphorylated and associated with v-Src in v-src-transformed fibroblasts

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7 January 2021

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

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7 January 2021

Dimerization of cell surface receptors in signal transduction

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7 January 2021

EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

Complex complexes: signaling at the TCR.

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7 January 2021

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

1 reference

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7 January 2021

Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Thrombopoietin induces activation of at least two distinct signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

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7 January 2021

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

1 reference

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7 January 2021

Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells

1 reference

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7 January 2021

Regulation of the association of p120cbl with Grb2 in Jurkat T cells

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7 January 2021

The GRB2/Sem-5 adaptor protein

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7 January 2021

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

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7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

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7 January 2021

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

1 reference

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7 January 2021

Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)

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7 January 2021

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

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7 January 2021

Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.

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7 January 2021

Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia

1 reference

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7 January 2021

The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner

1 reference

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7 January 2021

Crk interacts with tyrosine-phosphorylated p116 upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

1 reference

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7 January 2021

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

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7 January 2021

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7 January 2021

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

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7 January 2021

14-3-3 proteins on the MAP

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7 January 2021

Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function

1 reference

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7 January 2021

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells

1 reference

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7 January 2021

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1 reference

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7 January 2021

Crystal structure of the zeta isoform of the 14-3-3 protein

1 reference

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7 January 2021

Activation-modulated association of 14-3-3 proteins with Cbl in T cells

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7 January 2021

Bcr and Raf form a complex in vivo via 14-3-3 proteins

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7 January 2021

14-3-3 proteins associate with cdc25 phosphatases

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7 January 2021

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

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7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

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7 January 2021

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity

1 reference

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7 January 2021

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

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7 January 2021

p21ras mediates control of IL-2 gene promoter function in T cell activation.

1 reference

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7 January 2021

Multiple p21ras effector pathways regulate nuclear factor of activated T cells.

1 reference

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7 January 2021

p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells

1 reference

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7 January 2021

LET-23-mediated signal transduction during Caenorhabditis elegans development

1 reference

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7 January 2021

Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

1 reference

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7 January 2021

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

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7 January 2021

Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2897%2900179-4

7 January 2021

10.1016/S0898-6568(97)00179-4

Identifiers

DOI

1 reference

24 September 2017

1 reference