CD28 as a molecular amplifier extending TCR ligation and signaling capabilities. (Q40761126)

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5 December 2019

title

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities (English)

1 reference

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5 December 2019

1

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5 December 2019

Giorgio Mangino

3

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5 December 2019

author name string

G Attal-Bonnefoy

2

1 reference

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5 December 2019

S Mise-Omata

4

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5 December 2019

O Acuto

5

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5 December 2019

language of work or name

English

0 references

publication date

1 December 2001

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5 December 2019

number of pages

11

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inferred from page(s)

published in

Immunity

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5 December 2019

volume

15

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5 December 2019

issue

6

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5 December 2019

page(s)

935-945

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CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

5 December 2019

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CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

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7 January 2021

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

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Characteristics of antigen-independent and antigen-dependent interaction of dendritic cells with CD4+ T cells

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7 January 2021

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

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7 January 2021

Duration of TCR stimulation determines costimulatory requirement of T cells

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7 January 2021

CD28/B7 system of T cell costimulation

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7 January 2021

Tec kinases: modulators of lymphocyte signaling and development

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7 January 2021

The structural basis of T cell activation by superantigens.

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7 January 2021

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

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7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

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7 January 2021

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

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7 January 2021

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.

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7 January 2021

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

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7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

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7 January 2021

Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association

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7 January 2021

CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line

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7 January 2021

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

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7 January 2021

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

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7 January 2021

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

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7 January 2021

Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells

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7 January 2021

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

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7 January 2021

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7 January 2021

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

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7 January 2021

CD28 ligation induces tyrosine phosphorylation of Pyk2 but not Fak in Jurkat T cells

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7 January 2021

CD28 affects the earliest signaling events generated by TCR engagement

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7 January 2021

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

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7 January 2021

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

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7 January 2021

T cell antigen-receptor signal transduction

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7 January 2021

T cell activation determined by T cell receptor number and tunable thresholds.

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

CD28: a signalling perspective.

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7 January 2021

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

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7 January 2021

The role of Tec protein-tyrosine kinase in T cell signaling

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7 January 2021

Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain

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7 January 2021

CD28 co-stimulates TCR/CD3-induced phosphoinositide turnover in human T lymphocytes

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7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

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7 January 2021

10.1016/S1074-7613(01)00244-8

Identifiers

DOI

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release_25qfnm2nybe75iyuydlzorbkea

5 December 2019

Fatcat ID

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Fatcat

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24 November 2022

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