Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system. (Q40565579)

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27 December 2019

title

Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system (English)

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27 December 2019

0 references

2

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27 December 2019

Gadi Turgeman

4

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27 December 2019

author name string

Yossi Gafni

1

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27 December 2019

Yoram Zilberman

3

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27 December 2019

Florence Apparailly

5

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27 December 2019

Hagit Yotvat

6

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27 December 2019

Zulma Gazit

8

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27 December 2019

Christian Jorgensen

9

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27 December 2019

Dan Gazit

10

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27 December 2019

Eithan Galun

7

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publication date

1 April 2004

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27 December 2019

volume

9

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issue

4

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27 December 2019

page(s)

587-595

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The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Regulation of differentiation pathway of skeletal mesenchymal cells in cell lines by transforming growth factor-beta superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Novel regulators of bone formation: molecular clones and activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Recombinant human bone morphogenetic protein induces bone formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Recombinant human bone morphogenetic protein (rhBMP) induced heterotopic bone development in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Exogenously regulated stem cell-mediated gene therapy for bone regeneration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

The kinetics of rAAV integration in the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Molecular imaging of the skeleton: quantitative real-time bioluminescence monitoring gene expression in bone repair and development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Inducible long-term gene expression in brain with adeno-associated virus gene transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Tetracycline-inducible transgene expression mediated by a single AAV vector.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

An in vivo doxycycline-controlled expression system for functional studies of the retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Regulation of gene expression in adeno-associated virus vectors in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Glucose-responsive gene delivery in pancreatic Islet cells via recombinant adeno-associated viral vectors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Dose response to a single intramuscular injection of recombinant adeno-associated virus-erythropoietin in monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Long-term systemic therapy of Fabry disease in a knockout mouse by adeno-associated virus-mediated muscle-directed gene transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Mechanisms leading to sustained reversion of beta-thalassemia in mice by doxycycline-controlled Epo delivery from muscles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Long-term correction of glycogen storage disease type II with a hybrid Ad-AAV vector

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Novel tools for production and purification of recombinant adenoassociated virus vectors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Gene delivery to the myocardium by intrapericardial injection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

SV40-transformed simian cells support the replication of early SV40 mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Analysis of osteocalcin expression in transgenic mice reveals a species difference in vitamin D regulation of mouse and human osteocalcin genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Visualizing gene expression in living mammals using a bioluminescent reporter.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Imaging transgene expression in live animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Tyrosine kinase inhibitor AG18 arrests follicle-stimulating hormone-induced granulosa cell differentiation: use of reverse transcriptase-polymerase chain reaction assay for multiple messenger ribonucleic acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Cloning and characterization of a cDNA coding for mouse placental alkaline phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

A microtomographic system for the nondestructive evaluation of bone architecture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

Quantification of periapical bone destruction in mice by micro-computed tomography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.12.009

10.1016/J.YMTHE.2003.12.009

7 January 2021

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release_toytmvbm4vhpphuqbebedxr7pi

27 December 2019

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