Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. (Q40478337)

20 September 2017

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title

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. (English)

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20 September 2017

Ui M

1

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20 September 2017

Okada T

series ordinal

2

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20 September 2017

Hazeki K

series ordinal

3

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20 September 2017

Hazeki O

series ordinal

4

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20 September 2017

publication date

1 August 1995

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20 September 2017

number of pages

5

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Trends in Biochemical Sciences

inferred from page(s)

published in

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20 September 2017

volume

20

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20 September 2017

issue

8

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20 September 2017

page(s)

303-307

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Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues

20 September 2017

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7 January 2021

Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation

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7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

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Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin

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7 January 2021

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

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7 January 2021

Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase

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Modular organization of T4 DNA polymerase. Evidence from phylogenetics

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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Structure, regulation and function of phosphoinositide 3-kinases

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7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts

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7 January 2021

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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7 January 2021

New roles for G-protein beta gamma-dimers in transmembrane signalling.

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7 January 2021

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

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A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase.

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Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells

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Identification of a phosphatidylinositol 3-hydroxy kinase in plant cells: association with the cytoskeleton

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

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7 January 2021

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

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7 January 2021

Some unique characteristics of thylakoid unisite ATPase

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7 January 2021

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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7 January 2021

Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002.

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7 January 2021

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

The activation of phosphatidylinositol 3-kinase by Ras

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7 January 2021

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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7 January 2021

An essential role for Rac in Ras transformation

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7 January 2021

Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras

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7 January 2021

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

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7 January 2021

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7 January 2021

10.1016/S0968-0004(00)89056-8

Identifiers

DOI

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20 September 2017

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