Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells (Q40209258)

18 September 2017

title

Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells (English)

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18 September 2017

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Vesely DL

1

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18 September 2017

Hoffman B

series ordinal

2

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18 September 2017

Liebermann DA

series ordinal

3

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18 September 2017

language of work or name

English

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publication date

13 November 2006

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18 September 2017

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18 September 2017

volume

26

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18 September 2017

issue

21

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18 September 2017

page(s)

3041-3050

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Deregulated c-Myc prematurely recruits both Type I and II CD95/Fas apoptotic pathways associated with terminal myeloid differentiation

18 September 2017

cites work

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21 January 2018

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Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway

21 January 2018

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Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

21 January 2018

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Missing pieces in the NF-kappaB puzzle

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Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus

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21 January 2018

Signaling to NF-kappaB

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

21 January 2018

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Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

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Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Induction in myeloid leukemic cells of genes that are expressed in different normal tissues

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Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes

21 January 2018

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In vivo production of cytokines by bone marrow stromal cells and macrophages from patients with myelodysplastic syndrome

21 January 2018

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Twenty years of p53 research: structural and functional aspects of the p53 protein

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Death squads enlisted by the tumour suppressor p53.

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

21 January 2018

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Over-expression of Flt3 induces NF-kappaB pathway and increases the expression of IL-6.

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Disruption of differentiation in human cancer: AML shows the way.

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Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes

21 January 2018

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Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in Fc epsilon RI-mediated signal transduction

21 January 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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p53-independent apoptosis associated with c-Myc-mediated block in myeloid cell differentiation

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7 January 2021

Role of Mitochondria in Apoptosis

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7 January 2021

Differentiation primary response genes and proto-oncogenes as positive and negative regulators of terminal hematopoietic cell differentiation

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7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210109

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Dimensions Publication ID

18 September 2017

1023031992

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