Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes. (Q40199783)

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22 December 2019

title

Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes (English)

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22 December 2019

0 references

7

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22 December 2019

Michał Mińczuk

3

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22 December 2019

5

Yingying Zhang

1 reference

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22 December 2019

author name string

Fuyang Li

1

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22 December 2019

Monika Papworth

2

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22 December 2019

Christian Rohde

4

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22 December 2019

Sergei Ragozin

6

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22 December 2019

language of work or name

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6 December 2006

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22 December 2019

published in

Nucleic Acids Research

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22 December 2019

volume

35

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22 December 2019

issue

1

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22 December 2019

page(s)

100-112

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Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA

22 December 2019

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The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells

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Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells

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DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression

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22 September 2017

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Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1.

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Myc represses transcription through recruitment of DNA methyltransferase corepressor

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Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly

22 September 2017

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DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

22 September 2017

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Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription

22 September 2017

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Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.

22 September 2017

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22 September 2017

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Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

22 September 2017

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Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

22 September 2017

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Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

22 September 2017

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Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin

22 September 2017

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The herpes simplex virus VP16-induced complex: the makings of a regulatory switch

22 September 2017

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Targeted cytosine methylation for in vivo detection of protein-DNA interactions.

22 September 2017

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22 September 2017

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22 September 2017

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Expression of various genes is controlled by DNA methylation during mammalian development

22 September 2017

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Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors

22 September 2017

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Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors

22 September 2017

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Controlling the double helix

22 September 2017

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Chromatin modification and epigenetic reprogramming in mammalian development

22 September 2017

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Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

22 September 2017

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The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases

22 September 2017

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22 September 2017

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Molecular mechanisms of gene silencing mediated by DNA methylation

22 September 2017

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Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases

22 September 2017

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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

22 September 2017

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DNA methylation patterns and epigenetic memory

22 September 2017

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

22 September 2017

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Epigenetic reprogramming in mammalian development

22 September 2017

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The role of DNA methylation in mammalian epigenetics

22 September 2017

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22 September 2017

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22 September 2017

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

22 September 2017

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Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase

22 September 2017

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In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b

22 September 2017

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

22 September 2017

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Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production

22 September 2017

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

22 September 2017

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Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells

22 September 2017

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Mutations that inactivate a yeast transcriptional regulatory protein cluster in an evolutionarily conserved DNA binding domain

22 September 2017

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Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

22 September 2017

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CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

22 September 2017

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Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway

22 September 2017

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Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b

17 June 2018

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A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

17 June 2018

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Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein

17 June 2018

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Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.

17 June 2018

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Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

20 August 2018

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Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme

20 August 2018

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20 August 2018

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20 August 2018

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DNA methylation represses transcription in vivo.

20 August 2018

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Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17151075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytosine methylation targetted to pre-determined sequences

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17151075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modified Hirt procedure for rapid purification of extrachromosomal DNA from mammalian cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17151075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKL1035

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17151075%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17151075%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

17151075

1 reference