GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling. (Q40134750)

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30 December 2019

title

GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling (English)

1 reference

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30 December 2019

1

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30 December 2019

Massimiliano Agostini

5

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30 December 2019

Carlo Riccardi

7

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30 December 2019

author name string

Ornella Zollo

2

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30 December 2019

Alessandra Bastianelli

3

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30 December 2019

Cristina Marchetti

4

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30 December 2019

Rosa Di Virgilio

6

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30 December 2019

language of work or name

English

0 references

publication date

10 May 2007

1 reference

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Journal of Clinical Investigation

30 December 2019

published in

1 reference

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30 December 2019

volume

117

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30 December 2019

issue

6

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page(s)

1605-1615

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The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-beta-catenin complex

30 December 2019

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Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells

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Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells.

22 September 2017

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Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf

22 September 2017

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22 September 2017

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p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

22 September 2017

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A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death

22 September 2017

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Signal transduction from multiple Ras effectors

22 September 2017

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Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

22 September 2017

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Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

22 September 2017

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

22 September 2017

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Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells

22 September 2017

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

25 September 2017

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Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.

25 September 2017

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Cell cycle: routine role for Ras.

15 June 2018

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c-Myc and cyclin D3 (CcnD3) genes are independent targets for glucocorticoid inhibition of lymphoid cell proliferation

15 June 2018

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Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines

17 June 2018

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Glucocorticoid Receptor Counteracts Tumorigenic Activity of Akt in Skin through Interference with the Phosphatidylinositol 3-Kinase Signaling Pathway

20 August 2018

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Glucocorticoid action and novel mechanisms of steroid resistance: role of glucocorticoid receptor-interacting proteins for glucocorticoid responsiveness

20 August 2018

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RAS oncogenes: the first 30 years.

20 August 2018

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Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene.

20 August 2018

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Multiple ras effector pathways contribute to G(1) cell cycle progression

20 August 2018

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Increasing complexity of the Ras signaling pathway

20 August 2018

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Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17492054

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17492054

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17492054

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI30724

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17492054%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

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30 December 2019

PubMed publication ID

17492054

1 reference