Metabolic and antioxidant system alterations in an astrocytoma cell line challenged with mitochondrial DNA deletion (Q40121244)

17 September 2017

title

Metabolic and antioxidant system alterations in an astrocytoma cell line challenged with mitochondrial DNA deletion (English)

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17 September 2017

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Alfred Orina Isaac

1

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17 September 2017

Vikas V Dukhande

series ordinal

2

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17 September 2017

James C K Lai

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3

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17 September 2017

language of work or name

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12 June 2007

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17 September 2017

published in

Neurochemical Research

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17 September 2017

volume

32

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17 September 2017

issue

11

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17 September 2017

page(s)

1906-1918

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describes a project that uses

17 September 2017

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Role of oxidants in ischemic brain damage

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Ethidium bromide-induced loss of mitochondrial DNA from primary chicken embryo fibroblasts

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Biogenesis of mitochondria

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Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

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Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase

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Mitochondrial DNA. Methods and protocols. Introduction

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Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

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Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency.

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Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury

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Reversible tenfod reduction in mitochondria DNA content of human cells treated with ethidium bromide

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Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

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Mitochondrial H2O2 formation at site II.

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Mitochondrial complex I deficiency in Parkinson's disease

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Synaptic and non-synaptic mitochondria from rat brain: isolation and characterization

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Deletions of mitochondrial DNA in Kearns-Sayre syndrome

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Neurodegeneration or neuroprotection: the pivotal role of astrocytes

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Neurodegenerative disorders: the role of peroxynitrite

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The regeneration of reduced glutathione in rat forebrain mitochondria identifies metabolic pathways providing the NADPH required

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Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts

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Cytosolic and mitochondrial isoforms of NADP+-dependent isocitrate dehydrogenases are expressed in cultured rat neurons, astrocytes, oligodendrocytes and microglial cells

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Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication

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Manganese-induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells

1 reference

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Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite

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12 December 2020

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

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12 December 2020

Manganese treatment modulates the expression of peroxisome proliferator-activated receptors in astrocytoma and neuroblastoma cells

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Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster

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Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

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Glutathione Peroxidase Overexpression Inhibits CytochromecRelease and Proapoptotic Mediators to Protect Neurons From Experimental Stroke

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Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals

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Impairment of brain mitochondrial function by reactive nitrogen species: the role of glutathione in dictating susceptibility

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DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA.

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Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices

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DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

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Age-associated change in mitochondrial DNA damage

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The mitochondrial genotype can influence nuclear gene expression in yeast

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Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases.

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Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

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12 December 2020

10.1007/S11064-007-9380-3

Identifiers

DOI

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Dimensions Publication ID

17 September 2017

1012452508

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1 reference