Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels. (Q40054548)

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10 January 2020

title

Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels (English)

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10 January 2020

1

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10 January 2020

author name string

Jill L Thompson

series ordinal

2

1 reference

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10 January 2020

Trevor J Shuttleworth

series ordinal

3

1 reference

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10 January 2020

language of work or name

English

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publication date

8 November 2007

1 reference

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10 January 2020

number of pages

11

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based on heuristic

inferred from page(s)

published in

Journal of Physiology

1 reference

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volume

586

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issue

1

1 reference

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page(s)

185-195

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Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels

10 January 2020

cites work

1 reference

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Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels

14 September 2018

1 reference

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CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties.

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Biochemical and functional characterization of Orai proteins

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

CRACM1 multimers form the ion-selective pore of the CRAC channel.

14 September 2018

1 reference

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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

14 September 2018

1 reference

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Orai1 is an essential pore subunit of the CRAC channel

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

14 September 2018

1 reference

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Orai1 and STIM reconstitute store-operated calcium channel function

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

14 September 2018

1 reference

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Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

14 September 2018

1 reference

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CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

14 September 2018

1 reference

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STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

14 September 2018

1 reference

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STIM1, an essential and conserved component of store-operated Ca2+ channel function

14 September 2018

1 reference

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Store-operated calcium channels

14 September 2018

1 reference

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Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

ARC channels: a novel pathway for receptor-activated calcium entry

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Receptor-activated calcium entry channels--who does what, and when?

14 September 2018

1 reference

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Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Reciprocal regulation of capacitative and arachidonate-regulated noncapacitative Ca2+ entry pathways.

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Permeation of monovalent cations through the non-capacitative arachidonate-regulated Ca2+ channels in HEK293 cells. Comparison with endogenous store-operated channels.

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

The endoplasmic reticulum as one continuous Ca(2+) pool: visualization of rapid Ca(2+) movements and equilibration

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

I(ARC), a novel arachidonate-regulated, noncapacitative Ca(2+) entry channel

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

What drives calcium entry during [Ca2+]i oscillations?--challenging the capacitative model

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Store depletion and calcium influx

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Evidence for a non-capacitative Ca2+ entry during [Ca2+] oscillations

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

Depletion of intracellular calcium stores activates a calcium current in mast cells

14 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2375546

STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane

14 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17991693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Calcium release-activated calcium current in rat mast cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17991693

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2007.146258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17991693%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PMC publication ID

2375546

0 references

1 reference