HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway (Q39946864)

15 September 2017

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway (English)

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15 September 2017

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Dimmeler S

1

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15 September 2017

Aicher A

2

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15 September 2017

Vasa M

3

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15 September 2017

Mildner-Rihm C

4

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15 September 2017

Adler K

5

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15 September 2017

Tiemann M

6

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15 September 2017

Rütten H

7

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15 September 2017

Fichtlscherer S

8

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15 September 2017

Martin H

9

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15 September 2017

Zeiher AM

10

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15 September 2017

language of work or name

English

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publication date

1 August 2001

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Journal of Clinical Investigation

15 September 2017

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15 September 2017

108

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15 September 2017

3

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15 September 2017

391-397

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Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Angiogenesis in cancer and other diseases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

A role for hematopoietic stem cells in promoting angiogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

In vitro differentiation of endothelial cells from AC133-positive progenitor cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Stem cells: units of development, units of regeneration, and units in evolution

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Current perspectives on statins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Mechanisms of angiogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Isolation of putative progenitor endothelial cells for angiogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Angiogenesis in cancer, vascular, rheumatoid and other disease

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Evidence for circulating bone marrow-derived endothelial cells.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Enhanced endothelialization and microvessel formation in polyester grafts seeded with CD34(+) bone marrow cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Improvement in coronary flow reserve determined by positron emission tomography after 6 months of cholesterol-lowering therapy in patients with early stages of coronary atherosclerosis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209365

Targeting Rho in cardiovascular disease

20 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Akt takes center stage in angiogenesis signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/11489932

12 December 2020

Identifiers

DOI

10.1172/JCI200113152

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

11489932

1 reference