Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells (Q39740442)

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English	Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells (English)

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Europe PubMed Central

PubMed publication ID

14 September 2017

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David T. Curiel

9

object named as

D T Curiel

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14 September 2017

author name string

R Dash

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14 September 2017

I Dmitriev

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14 September 2017

Z-z Su

3

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14 September 2017

S K Bhutia

4

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14 September 2017

B Azab

5

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14 September 2017

N Vozhilla

6

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14 September 2017

A Yacoub

7

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14 September 2017

P Dent

8

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D Sarkar

10

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14 September 2017

P B Fisher

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publication date

12 February 2010

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14 September 2017

Cancer Gene Therapy

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14 September 2017

17

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14 September 2017

7

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14 September 2017

447-456

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14 September 2017

Highlights of contemporary issues in the medical management of prostate cancer

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21 January 2018

Gene therapy of prostate cancer: current and future directions

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Transductional and transcriptional targeting of adenovirus for clinical applications

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Characterization of infectivity of knob-modified adenoviral vectors in glioma.

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A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway

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21 January 2018

Engineering targeted viral vectors for gene therapy

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21 January 2018

Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism

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21 January 2018

The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

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21 January 2018

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

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21 January 2018

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

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21 January 2018

The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

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21 January 2018

Interleukin-10 and related cytokines and receptors

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21 January 2018

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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21 January 2018

Is mda-7/IL-24 a "magic bullet" for cancer?

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21 January 2018

Historical perspective and recent insights into our understanding of the molecular and biochemical basis of the antitumor properties of mda-7/IL-24.

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21 January 2018

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

1 reference

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21 January 2018

Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients

1 reference

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21 January 2018

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells

1 reference

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21 January 2018

Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

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21 January 2018

The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

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21 January 2018

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice

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21 January 2018

Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice

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Cancer statistics, 2008

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21 January 2018

Molecular markers and determinants of prostate cancer metastasis

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21 January 2018

Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class I expression in human prostate cancer cell lines: implications for gene therapy strategies.

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21 January 2018

Enhancement of Ad5-TRAIL cytotoxicity against renal cell carcinoma with histone deacetylase inhibitors

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21 January 2018

Histone deacetylase inhibitors enhance Ad5-TRAIL killing of TRAIL-resistant prostate tumor cells through increased caspase-2 activity

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21 January 2018

CD46 represents a target for adenoviral gene therapy of malignant glioma.

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21 January 2018

Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells

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21 January 2018

High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus

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Enhanced Adenovirus Infection of Melanoma Cells by Fiber-Modification: Incorporation of RGD Peptide or Ad5/3 Chimerism

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21 January 2018

Fiber-modified adenovirus vectors decrease liver toxicity through reduced IL-6 production

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21 January 2018

Ultrasound guided site specific gene delivery system using adenoviral vectors and commercial ultrasound contrast agents

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Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model

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Myc-driven murine prostate cancer shares molecular features with human prostate tumors

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Prostate cancer

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Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

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Prostate cancer: screening and early detection

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10.1038/CGT.2009.91

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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