Identifying the functional contribution of the defatty-acylase activity of SIRT6. (Q39670994)

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14 March 2020

title

Identifying the functional contribution of the defatty-acylase activity of SIRT6 (English)

1 reference

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14 March 2020

1

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14 March 2020

Nicole A Spiegelman

6

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14 March 2020

Jonathan H Shrimp

7

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14 March 2020

Hening Lin

9

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14 March 2020

author name string

Saba Khan

2

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14 March 2020

Hong Jiang

3

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14 March 2020

Marc A Antonyak

4

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14 March 2020

Xiao Chen

5

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14 March 2020

Richard A Cerione

8

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14 March 2020

publication date

20 June 2016

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14 March 2020

published in

Nature Chemical Biology

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14 March 2020

volume

12

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issue

8

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14 March 2020

page(s)

614-620

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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

14 March 2020

cites work

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Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

14 September 2017

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Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins

14 September 2017

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SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

14 September 2017

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Multiplex genome engineering using CRISPR/Cas systems

14 September 2017

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The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

14 September 2017

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The sirtuin SIRT6 regulates lifespan in male mice

14 September 2017

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Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells.

14 September 2017

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Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties

14 September 2017

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Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine

14 September 2017

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SIRT6 promotes DNA repair under stress by activating PARP1

14 September 2017

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Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

14 September 2017

1 reference

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Structure and biochemical functions of SIRT6.

14 September 2017

1 reference

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Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

14 September 2017

1 reference

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Human SIRT6 promotes DNA end resection through CtIP deacetylation

14 September 2017

1 reference

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Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases

14 September 2017

1 reference

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The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

14 September 2017

1 reference

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Functional dissection of SIRT6: identification of domains that regulate histone deacetylase activity and chromatin localization

14 September 2017

1 reference

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Microvesicles: messengers and mediators of tumor progression

14 September 2017

1 reference

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

14 September 2017

1 reference

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

14 September 2017

1 reference

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

14 September 2017

1 reference

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Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase

14 September 2017

1 reference

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

14 September 2017

1 reference

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Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

14 September 2017

1 reference

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SIRT6 exhibits nucleosome-dependent deacetylase activity

14 September 2017

1 reference

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The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals

17 June 2018

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The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability

21 August 2018

1 reference

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Robust fluorescent detection of protein fatty-acylation with chemical reporters.

21 August 2018

1 reference

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Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

21 August 2018

1 reference

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21 August 2018

Identifiers

DOI

10.1038/NCHEMBIO.2106

1 reference

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14 March 2020

1 reference

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14 March 2020

PubMed publication ID

27322069

1 reference