Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. (Q39659749)

13 September 2017

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. (English)

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13 September 2017

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10

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9 June 2020

Lucie Leveque

1

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9 June 2020

Kate A Markey

4

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9 June 2020

Katie E Lineburg

7

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9 June 2020

Kylie Anne Alexander

9

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9 June 2020

Bruce R Blazar

11

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9 June 2020

Geoffrey R Hill

12

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9 June 2020

Geoffrey E. Hill

13

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9 June 2020

Kelli P MacDonald

14

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9 June 2020

author name string

Motoko Koyama

2

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9 June 2020

Laetitia Le Texier

3

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9 June 2020

Melody Cheong

5

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9 June 2020

Rachel D Kuns

6

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9 June 2020

Bianca E Teal

8

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9 June 2020

language of work or name

English

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publication date

23 June 2016

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13 September 2017

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9 June 2020

volume

128

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9 June 2020

issue

6

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9 June 2020

page(s)

794-804

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Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

9 June 2020

cites work

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Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease.

14 September 2017

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α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics

14 September 2017

1 reference

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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

14 September 2017

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CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease

14 September 2017

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Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells

14 September 2017

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Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

14 September 2017

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Peripheral-blood stem cells versus bone marrow from unrelated donors

14 September 2017

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Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.

14 September 2017

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Interleukin-2 and regulatory T cells in graft-versus-host disease

14 September 2017

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Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells

14 September 2017

1 reference

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Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

14 September 2017

1 reference

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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

14 September 2017

1 reference

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Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease

14 September 2017

1 reference

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Enhancement of antigen-specific Treg vaccination in vivo

14 September 2017

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Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.

14 September 2017

1 reference

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STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model

14 September 2017

1 reference

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Immunosuppressive drugs and Tregs: a critical evaluation!

14 September 2017

1 reference

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Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease

14 September 2017

1 reference

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Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipper

14 September 2017

1 reference

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High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT

14 September 2017

1 reference

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Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

14 September 2017

1 reference

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Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

14 September 2017

1 reference

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Sclerodermatous graft-vs-host disease: clinical and pathological study of 17 patients

14 September 2017

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Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

14 September 2017

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

14 September 2017

1 reference

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Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

14 September 2017

1 reference

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Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease

25 September 2017

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HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.

15 June 2018

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Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo.

21 August 2018

1 reference

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A glucocorticoid amplifies IL-2-induced selective expansion of CD4(+)CD25(+)FOXP3(+) regulatory T cells in vivo and suppresses graft-versus-host disease after allogeneic lymphocyte transplantation.

21 August 2018

1 reference

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Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation

21 August 2018

1 reference

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DNA methylation controls Foxp3 gene expression

21 August 2018

1 reference

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Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations

21 August 2018

1 reference

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Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD.

21 August 2018

1 reference

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CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

21 August 2018

1 reference

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Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients.

21 August 2018

1 reference

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Glucocorticoid-Induced Leucine Zipper Enhanced Expression in Dendritic Cells Is Sufficient To Drive Regulatory T Cells Expansion In Vivo

21 August 2018

1 reference

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Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

2 December 2018

1 reference

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Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

2 December 2018

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IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract

2 December 2018

1 reference

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Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD

2 December 2018

1 reference

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Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease

2 December 2018

1 reference

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Risk-factor analysis for predicting progressive- or quiescent-type chronic graft-versus-host disease in a patient cohort with a history of acute graft-versus-host disease after allogeneic stem cell transplantation

2 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

Natural killer (NK)-cell function and antileukemic activity of a large population of CD3+/CD8+ T cells expressing NK receptors for major histocompatibility complex class I after "three-loci" HLA-incompatible bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/27338097

12 December 2020

10.1182/BLOOD-2015-11-680876

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27338097%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27338097%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

27338097

1 reference