The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase (Q39454531)

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8 November 2019

title

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase (English)

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8 November 2019

1

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8 November 2019

Cécile Arrieumerlou

2

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8 November 2019

author name string

G Ku

3

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8 November 2019

B M Burgering

4

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8 November 2019

A Weiss

5

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8 November 2019

I M Kramer

6

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8 November 2019

language of work or name

English

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publication date

1 August 2000

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Molecular and Cellular Biology

8 November 2019

published in

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8 November 2019

volume

20

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8 November 2019

issue

15

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8 November 2019

page(s)

5469-5478

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Signalling through the insulin receptor

8 November 2019

cites work

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The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase

12 September 2017

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12 September 2017

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

12 September 2017

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

12 September 2017

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Mechanism of activation of protein kinase B by insulin and IGF-1

12 September 2017

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Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation

12 September 2017

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Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

12 September 2017

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

12 September 2017

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Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.

12 September 2017

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12 September 2017

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

12 September 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

12 September 2017

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Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.

12 September 2017

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

14 September 2017

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25 September 2017

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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21 August 2018

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2 December 2018

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https://pubmed.ncbi.nlm.nih.gov/10891487

12 December 2020

The protein interactions of the immunoglobulin receptor family tyrosine-based activation motifs present in the T cell receptor zeta subunits and the CD3 gamma, delta and epsilon chains

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12 December 2020

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

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12 December 2020

p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10891487

12 December 2020

10.1128/MCB.20.15.5469-5478.2000

Identifiers

DOI

1 reference

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8 November 2019

1 reference

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8 November 2019

PubMed publication ID

10891487

1 reference