Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax. (Q39093595)

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30 March 2020

title

Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax (English)

1 reference

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blastic plasmacytoid dendritic cell neoplasm

30 March 2020

main subject

0 references

Acute myeloid dendritic cell leukemia

1 reference

1 reference

1

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Lucía Cabal-Hierro

5

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16

Anthony Letai

1 reference

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15

Naveen Pemmaraju

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author name string

Jason Stephansky

2

1 reference

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Tianyu Cai

3

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Gabriel K Griffin

4

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Katsuhiro Togami

6

1 reference

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Leah J Hogdal

7

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Ilene Galinsky

8

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Elizabeth A Morgan

9

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Jon C Aster

10

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Matthew S Davids

11

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30 March 2020

Nicole R LeBoeuf

12

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Richard M Stone

13

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Andrew A Lane

17

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Marina Konopleva

14

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publication date

16 December 2016

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30 March 2020

1 reference

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volume

7

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issue

2

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page(s)

156-164

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describes a project that uses

30 March 2020

ImageQuant

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11 June 2022

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cites work

Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia

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Chemical parsing: Dissecting cell dependencies with a toolkit of selective BCL-2 family inhibitors

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Blastic plasmacytoid dendritic cell neoplasm: diagnostic criteria and therapeutical approaches

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Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia

9 September 2017

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Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

9 September 2017

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Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia

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Targeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm

9 September 2017

1 reference

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Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition.

9 September 2017

1 reference

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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia

9 September 2017

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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

9 September 2017

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Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study.

9 September 2017

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Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia

9 September 2017

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BH3 profiling--measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions

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9 September 2017

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9 September 2017

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A novel plasmacytoid dendritic cell line, CAL-1, established from a patient with blastic natural killer cell lymphoma.

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Long-term survival following autologous and allogeneic stem cell transplantation for blastic plasmacytoid dendritic cell neoplasm

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Validation and Implementation of a Custom Next-Generation Sequencing Clinical Assay for Hematologic Malignancies

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iBH3: simple, fixable BH3 profiling to determine apoptotic priming in primary tissue by flow cytometry

21 August 2018

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Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion.

21 August 2018

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Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm

21 August 2018

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CD4+, CD56+ DC2 acute leukemia is characterized by recurrent clonal chromosomal changes affecting 6 major targets: a study of 21 cases by the Groupe Francais de Cytogenetique Hematologique

2 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27986708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27986708

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12 December 2020

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Identifiers

DOI

10.1158/2159-8290.CD-16-0999

1 reference

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30 March 2020

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30 March 2020

PubMed publication ID

27986708

1 reference