MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia (Q38294261)

1 September 2017

title

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia (English)

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1 September 2017

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8

Eric S Lander

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5

Monique L den Boer

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4

Rob Pieters

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9

Todd R Golub

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1 September 2017

Scott A Armstrong

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Jane E Staunton

2

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1 September 2017

Lewis B Silverman

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Mark D Minden

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1 September 2017

Stephen E Sallan

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Stanley J Korsmeyer

10

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1 September 2017

language of work or name

English

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publication date

3 December 2001

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1 September 2017

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1 September 2017

volume

30

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1 September 2017

issue

1

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1 September 2017

page(s)

41-47

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The critical role of chromosome translocations in human leukemias.

1 September 2017

cites work

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The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

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Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

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Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product

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Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

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Altered Hox expression and segmental identity in Mll-mutant mice

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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

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7 January 2021

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

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B cell development pathways

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Role of helix-loop-helix proteins in lymphocyte development

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Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1.

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Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

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Expression of rhombotin 2 in normal and leukaemic haemopoietic cells

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Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor

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Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity

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Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

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Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

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Multilineage gene expression precedes commitment in the hemopoietic system

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7 January 2021

Bipotential B-macrophage progenitors are present in adult bone marrow.

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7 January 2021

Bipotential precursors of B cells and macrophages in murine fetal liver

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7 January 2021

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

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7 January 2021

The B/macrophage cell: an elusive link between CD5+ B lymphocytes and macrophages

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7 January 2021

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

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Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants

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7 January 2021

All-trans-retinoic acid in acute promyelocytic leukemia

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7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

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7 January 2021

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

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Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

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7 January 2021

Sensitivity of FISH in detection of MLL translocations

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7 January 2021

Identifiers

DOI

10.1038/NG765

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1 September 2017

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