HIV reservoirs and strategies for eradication (Q37976293)

26 August 2017

title

HIV reservoirs and strategies for eradication (English)

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26 August 2017

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3

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26 August 2017

Miranda Z Smith

1

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Fiona Wightman

object named as

Fiona Wightman

series ordinal

2

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publication date

1 March 2012

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26 August 2017

published in

Current HIV/AIDS reports

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26 August 2017

volume

9

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26 August 2017

issue

1

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26 August 2017

page(s)

5-15

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

26 August 2017

cites work

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Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

21 January 2018

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HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

21 January 2018

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Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

21 January 2018

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Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy

21 January 2018

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CD4⁺ recent thymic emigrants are infected by HIV in vivo, implication for pathogenesis.

21 January 2018

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HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.

21 January 2018

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HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells

21 January 2018

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Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues

21 January 2018

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Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

21 January 2018

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Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

21 January 2018

1 reference

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Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy

21 January 2018

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Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy

21 January 2018

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The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy

21 January 2018

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CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection

21 January 2018

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HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment

21 January 2018

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Follicular dendritic cells and human immunodeficiency virus type 1 transcription in CD4+ T cells

21 January 2018

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Low frequency of intermittent HIV-1 semen excretion in patients treated with darunavir-ritonavir at 600/100 milligrams twice a day plus two nucleoside reverse transcriptase inhibitors or monotherapy

21 January 2018

1 reference

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Genital tract HIV-1 RNA shedding among women with below detectable plasma viral load

21 January 2018

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Penetration of atazanavir in seminal plasma of men infected with human immunodeficiency virus type 1.

21 January 2018

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Infection of semen-producing organs by SIV during the acute and chronic stages of the disease

21 January 2018

1 reference

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Susceptibility of human testis to human immunodeficiency virus-1 infection in situ and in vitro

21 January 2018

1 reference

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Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS

21 January 2018

1 reference

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Replication-competent simian immunodeficiency virus (SIV) Gag escape mutations archived in latent reservoirs during antiretroviral treatment of SIV-infected macaques

21 January 2018

1 reference

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A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy

21 January 2018

1 reference

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A simian immunodeficiency virus macaque model of highly active antiretroviral treatment: viral latency in the periphery and the central nervous system

21 January 2018

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New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma

21 January 2018

1 reference

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Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

21 January 2018

1 reference

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HIV cure and eradication: how will we get from the laboratory to effective clinical trials?

21 January 2018

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Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy

21 January 2018

1 reference

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Human endogenous retrovirus K (HML-2) elements in the plasma of people with lymphoma and breast cancer

21 January 2018

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Detection of HERV-K(HML-2) viral RNA in plasma of HIV type 1-infected individuals

21 January 2018

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HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

21 January 2018

1 reference

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HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure

21 January 2018

1 reference

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Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue

21 January 2018

1 reference

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R5 HIV env and vesicular stomatitis virus G protein cooperate to mediate fusion to naive CD4+ T Cells.

21 January 2018

1 reference

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HIV-1 actively replicates in naive CD4(+) T cells residing within human lymphoid tissues

21 January 2018

1 reference

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Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

21 January 2018

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An in vitro system to model the establishment and reactivation of HIV-1 latency.

21 January 2018

1 reference

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Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

HIV integration site distributions in resting and activated CD4+ T cells infected in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Gene silencing in HIV-1 latency by polycomb repressive group

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Novel histone deacetylase inhibitors CG05 and CG06 effectively reactivate latently infected HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Cell line-dependent variability in HIV activation employing DNMT inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Combinatorial latency reactivation for HIV-1 subtypes and variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner

21 January 2018

1 reference

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Activation of latent HIV using drug-loaded nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

21 January 2018

1 reference

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High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Hit-and-run stimulation: a novel concept to reactivate latent HIV-1 infection without cytokine gene induction

21 January 2018

1 reference

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PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Episomal viral cDNAs identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure

21 January 2018

1 reference

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Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads

21 January 2018

1 reference

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Investigating signs of recent evolution in the pool of proviral HIV type 1 DNA during years of successful HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

HIV-1 drug resistance profiles in children and adults with viral load of <50 copies/ml receiving combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy

21 January 2018

1 reference

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Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0108-2

Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

CpG methylation controls reactivation of HIV from latency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Phenotypic heterogeneity of human endogenous retrovirus particles produced by teratocarcinoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

The emerging race to cure HIV infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

Immune reconstitution in the sigmoid colon after long-term HIV therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249405

12 December 2020

10.1007/S11904-011-0108-2

Identifiers

DOI

1 reference

26 August 2017

1 reference