Rhabdomyosarcomas: an overview on the experimental animal models. (Q37973827)

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19 January 2020

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3 December 2020

Rhabdomyosarcomas: an overview on the experimental animal models (English)

1 reference

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7 August 2019

biomedical investigative technique

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19 September 2019

1 reference

3 December 2020

4

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19 January 2020

author name string

Alessandra Zanola

1

1 reference

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19 January 2020

Stefania Rossi

2

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19 January 2020

Fiorella Faggi

3

1 reference

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19 January 2020

Alessandro Fanzani

5

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publication date

1 July 2012

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7 August 2019

19 September 2019

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19 January 2020

3 December 2020

Journal of Cellular and Molecular Medicine

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7 August 2019

19 September 2019

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19 January 2020

issue

7

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19 January 2020

page(s)

1377-1391

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Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53-deficient mice

19 January 2020

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Rhabdomyosarcomas in aging A/J mice

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Pyrrolizidine alkaloids in food: a spectrum of potential health consequences.

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Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma

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Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

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The first 30 years of p53: growing ever more complex

6 September 2017

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Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2005

6 September 2017

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The signal pathways in azoxymethane-induced colon cancer and preventive implications

6 September 2017

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Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts

6 September 2017

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MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.

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Rhabdomyosarcoma in patients with constitutional mismatch-repair-deficiency syndrome

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Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group

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The role of IGF-1R in pediatric malignancies

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Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?

6 September 2017

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PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

6 September 2017

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PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.

6 September 2017

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PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound

6 September 2017

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RAGE expression in rhabdomyosarcoma cells results in myogenic differentiation and reduced proliferation, migration, invasiveness, and tumor growth.

6 September 2017

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Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

6 September 2017

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Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

6 September 2017

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Role for amplification and expression of glypican-5 in rhabdomyosarcoma

6 September 2017

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p53 family members in myogenic differentiation and rhabdomyosarcoma development

6 September 2017

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Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors

6 September 2017

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Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

6 September 2017

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Germline mutations in HRAS proto-oncogene cause Costello syndrome

6 September 2017

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New genetic tactics to model alveolar rhabdomyosarcoma in the mouse

6 September 2017

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MyoD and the transcriptional control of myogenesis

6 September 2017

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Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats

6 September 2017

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Ptc1 heterozygous knockout mice as a model of multi-organ tumorigenesis

6 September 2017

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Nevoid basal cell carcinoma (Gorlin) syndrome

6 September 2017

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Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

6 September 2017

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The Hedgehog response network: sensors, switches, and routers

6 September 2017

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Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression

6 September 2017

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Pyrrolizidine alkaloids--genotoxicity, metabolism enzymes, metabolic activation, and mechanisms

6 September 2017

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Soft tissue sarcomas of childhood

6 September 2017

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The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

6 September 2017

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Molecular pathogenesis of rhabdomyosarcoma

6 September 2017

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Mutations in SUFU predispose to medulloblastoma

6 September 2017

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Scatter-factor and semaphorin receptors: cell signalling for invasive growth

6 September 2017

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Dysregulation of Met receptor tyrosine kinase activity in invasive tumors

6 September 2017

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Hedgehog signaling in animal development: paradigms and principles

6 September 2017

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Identification of new genes related to the myogenic differentiation arrest of human rhabdomyosarcoma cells

6 September 2017

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The INK4a/ARF network in tumour suppression

6 September 2017

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PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma

6 September 2017

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AP-1 in mouse development and tumorigenesis

6 September 2017

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Molecular distinction between specification and differentiation in the myogenic basic helix-loop-helix transcription factor family

6 September 2017

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Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

6 September 2017

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Animal models for muscular dystrophy: valuable tools for the development of therapies

6 September 2017

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Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma

6 September 2017

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Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

6 September 2017

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cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

6 September 2017

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Rhabdomyosarcoma--working out the pathways

6 September 2017

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Polycyclic aromatic hydrocarbons in carcinogenesis

6 September 2017

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Progressive muscular dystrophy in alpha-sarcoglycan-deficient mice

6 September 2017

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

6 September 2017

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Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples

6 September 2017

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Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

6 September 2017

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Gains, losses, and amplification of genomic material in rhabdomyosarcoma analyzed by comparative genomic hybridization

6 September 2017

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The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein.

6 September 2017

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Pax3 modulates expression of the c-Met receptor during limb muscle development

6 September 2017

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Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments

6 September 2017

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Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

6 September 2017

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Dystrophin protects the sarcolemma from stresses developed during muscle contraction

6 September 2017

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A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

6 September 2017

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Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

6 September 2017

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Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

6 September 2017

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Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma

6 September 2017

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Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

6 September 2017

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Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

6 September 2017

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Tumor spectrum analysis in p53-mutant mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

X chromosome-linked muscular dystrophy (mdx) in the mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Organ-specific carcinogenesis in rats by methyl- and ethylazoxyalkanes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

In vitro differentiation of rhabdomyosarcomas induced by nickel or by Moloney murine sarcoma virus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Animal models of muscular dystrophy – what can they teach us?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Cellular progression of neoplasia in the subcutis of mice after implantation of 3,4-benzpyrene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Differentiation of human rhabdomyosarcoma RD cells is regulated by reciprocal, functional interactions between myostatin, p38 and extracellular regulated kinase signalling pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

ErbB2 is required for muscle spindle and myoblast cell survival.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

RAS signaling dysregulation in human embryonal Rhabdomyosarcoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

The MET receptor tyrosine kinase contributes to invasive tumour growth in rhabdomyosarcomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: the Children's Oncology Group experience

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

The cooperative transforming effects of PAX3-FKHR and IGF-II on mouse myoblasts.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Vascular endothelial growth factor acts in an autocrine manner in rhabdomyosarcoma cell lines and can be inhibited with all-trans-retinoic acid

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Inhibition of autocrine secretion of myostatin enhances terminal differentiation in human rhabdomyosarcoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Tumors in Rubinstein-Taybi syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Induction of testicular sarcomas in Fischer rats by intratesticular injection of nickel subsulfide

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

TGF-beta autocrine loop regulates cell growth and myogenic differentiation in human rhabdomyosarcoma cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Emerging multipotent aspects of hepatocyte growth factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

A common region of loss of heterozygosity in Wilms' tumor and embryonal rhabdomyosarcoma distal to the D11S988 locus on chromosome 11p15.5.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Developmental models of brain dysfunctions induced by targeted cellular ablations with methylazoxymethanol

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Carcinogenesis by benzenediazonium sulfate in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Molecular genetics and pathogenesis of rhabdomyosarcoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

N-methyl-N'-nitro-N-nitrosoguanidine-induced neoplasms in medaka (Oryzias latipes).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, and CDKN2C) in childhood rhabdomyosarcoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Pathogenesis of a rhabdomyosarcoma (undifferentiated type) in rats induced by a murine sarcoma virus (Moloney).

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

N-ras gene activation in the RD human rhabdomyosarcoma cell line.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Detection of point mutations in N-ras and K-ras genes of human embryonal rhabdomyosarcomas using oligonucleotide probes and the polymerase chain reaction.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Tumor induction by 4-(methyl)benzenediazonium sulfate in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Somatic reversion/suppression of the mouse mdx phenotype in vivo.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Muscle-specific gene expression in rhabdomyosarcomas and stages of human fetal skeletal muscle development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Epstein-Barr virus activators, mutagens and volatile nitrosamines in preserved food samples from high-risk areas for nasopharyngeal carcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Frequency and diversity of p53 mutations in childhood rhabdomyosarcoma.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Rhabdomyosarcoma. A new classification scheme related to prognosis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Comparing adult and pediatric rhabdomyosarcoma in the surveillance, epidemiology and end results program, 1973 to 2005: an analysis of 2,600 patients

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Transgenic model of cardiac rhabdomyosarcoma formation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Loss of suppressor-of-fused function promotes tumorigenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Uniparental disomy at chromosome 11p15.5 followed by HRAS mutations in embryonal rhabdomyosarcoma: lessons from Costello syndrome.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

THE EFFECT OF PHYSICAL FORM OF IMPLANT ON NICKEL SULPHIDE TUMOURIGENESIS IN THE RAT

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Metal carcinogenesis. II. A study on the carcinogenic activity of cobalt, copper, iron, and nickel compounds.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

An anti-apoptotic role for NGF receptors in human rhabdomyosarcoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Cytogenetic abnormalities in 42 rhabdomyosarcoma: a United Kingdom Cancer Cytogenetics Group Study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Neoplasia in zebrafish (Danio rerio) treated with N-methyl-N'-nitro-N-nitrosoguanidine by three exposure routes at different developmental stages.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Neoplasia in zebrafish (Danio rerio) treated with 7,12-dimethylbenz[a]anthracene by two exposure routes at different developmental stages.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Role of the INK4a locus in tumor suppression and cell mortality.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Development of rhabdomyosarcoma in HER-2/neu transgenic p53 mutant mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Expression of HER/erbB family of receptor tyrosine kinases and induction of differentiation by glial growth factor 2 in human rhabdomyosarcoma cells

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Dystrophin-deficient mdx muscle fibers are preferentially vulnerable to necrosis induced by experimental lengthening contractions

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823208

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome

1 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Dysferlin deletion in SJL mice (SJL-Dysf) defines a natural model for limb girdle muscular dystrophy 2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Rhabdomyosarcoma development in mice lacking Trp53 and Fos

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Tumour-suppressor activity of H19 RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2011.01518.X

Induction of sarcomas by a single subcutaneous injection of 7,12-dimethylbenz[a]anthracene into neonatal male Sprague-Dawley rats: histopathological and immunohistochemical analyses

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

HGF/SF is present in normal adult skeletal muscle and is capable of activating satellite cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

H-ras and K-ras mutations in soft tissue sarcoma: comparative studies of sarcomas from Korean and American patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Tissue-specific expression of SV40 in tumors associated with the Li-Fraumeni syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Genetic modeling of human rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

MYCN gene amplification in rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Risk of Soft Tissue Sarcomas by Individual Subtype in Survivors of Hereditary Retinoblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

N-myc gene amplification in rhabdomyosarcoma detected by fluorescence in situ hybridization: its correlation with histologic features

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Soft-tissue sarcomas in children and adolescents with neurofibromatosis type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Chromosomal imbalances in pleomorphic rhabdomyosarcomas and identification of the alveolar rhabdomyosarcoma-associated PAX3-FOXO1A fusion gene in one case

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Dehydroretronecine-induced rhabdomyosarcomas in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Rapid induction of sarcomas in rats by combination of nickel sulfide and 3,4-benzpyrene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Concise handbook of familial cancer susceptibility syndromes - second edition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Up-regulation of MET but not neural cell adhesion molecule expression by the PAX3-FKHR fusion protein in alveolar rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

N-myc gene is amplified in alveolar rhabdomyosarcomas (RMS) but not in embryonal RMS

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Fishing for the origins of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Transcriptional regulation of IGF-I receptor gene expression by the PAX3-FKHR oncoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Cancer induction in mice by 4-hydroxybenzenediazonium sulfate of the Agaricus xanthodermus mushroom

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Cylindrical laminated bodies in nickel-subsulphide-induced rhabdomyosarcoma in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Experimental induction of rhabdomyosarcoma in mice with fractionated doses of beta-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

H-ras-1 point mutations in soft tissue sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

You can win by losing: p53 mutations in rhabdomyosarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

The molecular basis of muscular dystrophy in the mdx mouse: a point mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22225829

12 December 2020

10.1111/J.1582-4934.2011.01518.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225829%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225829%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22225829

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225829%20AND%20SRC:MED&resulttype=core&format=json