Focal adhesion kinase and tumour angiogenesis (Q37943776)

25 August 2017

title

Focal adhesion kinase and tumour angiogenesis (English)

1 reference

25 August 2017

1 reference

Kairbaan Hodivala-Dilke

object named as

Kairbaan Hodivala-Dilke

series ordinal

2

0 references

author name string

Tanguy Lechertier

series ordinal

1

1 reference

25 August 2017

language of work or name

1 reference

23 November 2011

1 reference

25 August 2017

1 reference

25 August 2017

volume

226

1 reference

25 August 2017

issue

2

1 reference

25 August 2017

page(s)

404-412

1 reference

Angiogenesis in health and disease

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Integrins in angiogenesis: multitalented molecules in a balancing act.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Integrin-regulated FAK-Src signaling in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

FERM domain interaction promotes FAK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Structural basis for the autoinhibition of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Signal transduction by focal adhesion kinase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

RAFTK/Pyk2-mediated cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Src and focal adhesion kinase as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Cellular characterization of a novel focal adhesion kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Paradoxical roles of FAK in tumor cell migration and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Characterization of a novel focal adhesion kinase inhibitor in human platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

FAK regulates biological processes important for the pathogenesis of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Bioluminescent imaging study: FAK inhibitor, PF-562,271, preclinical study in PC3M-luc-C6 local implant and metastasis xenograft models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Conditional deletion of the focal adhesion kinase FAK alters remodeling of the blood-brain barrier in glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Endothelial FAK is required for tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Normalization of the vasculature for treatment of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Codon-improved Cre recombinase (iCre) expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPATH.3018

21 January 2018

Identifiers

DOI

10.1002/PATH.3018

1 reference

25 August 2017

1 reference