Vitamin D metabolism and signaling in the immune system (Q37918438)

25 August 2017

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title

Vitamin D metabolism and signaling in the immune system (English)

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25 August 2017

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1

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25 August 2017

publication date

1 March 2012

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Reviews in Endocrine and Metabolic Disorders

25 August 2017

published in

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25 August 2017

volume

13

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25 August 2017

issue

1

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25 August 2017

page(s)

21-29

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Cell defenses and the sunshine vitamin

25 August 2017

cites work

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Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase

21 January 2018

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21 January 2018

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Enzymes involved in the activation and inactivation of vitamin D.

21 January 2018

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Metabolism of vitamin D by human microsomal CYP2R1.

21 January 2018

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Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease

21 January 2018

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Redefining vitamin D insufficiency

21 January 2018

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High Prevalence of Vitamin D Inadequacy and Implications for Health

21 January 2018

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Prevalence of vitamin D insufficiency in an adult normal population

21 January 2018

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Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy

21 January 2018

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The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know

21 January 2018

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Why the IOM recommendations for vitamin D are deficient

21 January 2018

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Nuclear receptors and lipid physiology: opening the X-files

21 January 2018

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The pleiotropic actions of vitamin D.

21 January 2018

1 reference

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Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation

21 January 2018

1 reference

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Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes

21 January 2018

1 reference

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Genomic vitamin D signaling in breast cancer: Insights from animal models and human cells.

21 January 2018

1 reference

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The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Convergence of vitamin D and retinoic acid signalling at a common hormone response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Combinatorial control of gene expression by nuclear receptors and coregulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Activation of receptor activator of NF-kappaB ligand gene expression by 1,25-dihydroxyvitamin D3 is mediated through multiple long-range enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

A downstream intergenic cluster of regulatory enhancers contributes to the induction of CYP24A1 expression by 1alpha,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D in the treatment of pulmonary tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D signaling, infectious diseases, and regulation of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Microbiota regulates immune defense against respiratory tract influenza A virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D: modulator of the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Immune-modifying properties of topical vitamin D: Focus on dendritic cells and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Getting under the skin: the immunogenetics of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Multiple sclerosis and vitamin D: a review and recommendations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Human defensins and LL-37 in mucosal immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Therapeutic implications of the TLR and VDR partnership

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D as an inducer of cathelicidin antimicrobial peptide expression: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D receptor as an intestinal bile acid sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin beta2 innate immune pathway defective in Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

The genetics and immunopathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Crohn's disease: an immune deficiency state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Mechanisms of disease: vitamin D and inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Seasonal variation in flares of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Vitamin D and the immune system: new perspectives on an old theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Calcium and Vitamin D in Sarcoidosis: How to Assess and Manage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Cathelicidins, multifunctional peptides of the innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Hypovitaminosis D in Medical Inpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11154-011-9195-Z

Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994.

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Nuclear factor of activated T cells (NFAT) as a molecular target for 1alpha,25-dihydroxyvitamin D3-mediated effects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Vitamin D3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

IOM endorses vitamin D, calcium only for bone health, dispels deficiency claims

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Vitamin D induces the antimicrobial protein hCAP18 in human skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Seasonal variations in onset of symptoms in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Functional antagonism between vitamin D3 and retinoic acid in the regulation of CD14 and CD23 expression during monocytic differentiation of U-937 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Racial differences in susceptibility to infection by Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Crohn's disease as an immune deficiency?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Innate immunity to pathogens: diversity in receptors for microbial recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Seasonal change in the exacerbations of Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Toll-like receptors and innate immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

From bench to bedside--translational research in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Cod and the consumptive: a brief history of cod-liver oil in the treatment of pulmonary tuberculosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845364

12 December 2020

10.1007/S11154-011-9195-Z

Identifiers

DOI

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25 August 2017

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