The application of DNA and RNA G-quadruplexes to therapeutic medicines. (Q37905612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

1 reference

title

The application of DNA and RNA G-quadruplexes to therapeutic medicines (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Gary N Parkinson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

publication date

25 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

published in

Chemical Society Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

5867-5892

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

8 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Normal human chromosomes have long G-rich telomeric overhangs at one end

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Induction of duplex to G-quadruplex transition in the c-myc promoter region by a small molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Prevalence of quadruplexes in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Highly prevalent putative quadruplex sequence motifs in human DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplexes in promoters throughout the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplexes: the beginning and end of UTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Helix formation by guanylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Predicting and understanding the stability of G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomeres do D-loop-T-loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

NMR solution structures of LNA (locked nucleic acid) modified quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Identification of a new G-quadruplex motif in the KRAS promoter and design of pyrene-modified G4-decoys with antiproliferative activity in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Solution structure of a locked nucleic acid modified quadruplex: introducing the V4 folding topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Solution structure of a parallel-stranded G-quadruplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Crystal structure of four-stranded Oxytricha telomeric DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The high-resolution crystal structure of a parallel-stranded guanine tetraplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of the first parallel DNA quadruplex-drug complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of a G-quadruplex-ligand complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structural basis of DNA quadruplex recognition by an acridine drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structural basis for binding of porphyrin to human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex recognition by quinacridines: a SAR, NMR, and biological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structural basis of telomeric RNA quadruplex--acridine ligand recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex DNA assemblies: loop length, cation identity, and multimer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Base-tetrad swapping results in dimerization of RNA quadruplexes: implications for formation of the i-motif RNA octaplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Making sense of G‐quadruplex and i‐motif functions in oncogene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Gene function correlates with potential for G4 DNA formation in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Selection for the G4 DNA motif at the 5' end of human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

pH-dependent structures of an i-motif DNA in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA tetraplex formation in the control region of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Putative DNA quadruplex formation within the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Coexistence of two distinct G-quadruplex conformations in the hTERT promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structural diversity and extreme stability of unimolecular Oxytricha nova telomeric G-quadruplex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Crystal structure of parallel quadruplexes from human telomeric DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Models of macromolecular crowding effects and the need for quantitative comparisons with experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Translational recoding induced by G-rich mRNA sequences that form unusual structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Preferential binding of fd gene 5 protein to tetraplex nucleic acid structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure in nascent RNA leads to termination of slippage transcription by T7 RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

TERRA transcripts are bound by a complex array of RNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex formation by human telomeric repeats-containing RNA in Na+ solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Human telomeric RNA r(UAGGGU) sequence forms parallel tetraplex structure with U-quartet

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Monomorphic RNA G-quadruplex and polymorphic DNA G-quadruplex structures responding to cellular environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Human telomere quadruplex: refolding and selection of individual conformers via RNA/DNA chimeric editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A Novel Yeast Gene Product, G4p1, with a Specific Affinity for Quadruplex Nucleic Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomeric repeat-containing RNA structure in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Small-molecule-mediated G-quadruplex isolation from human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The BCL-2 5′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Repression of translation of human estrogen receptor alpha by G-quadruplex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

FMRP mediates mGluR5-dependent translation of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-Quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Nucleic acid aptamers based on the G-quadruplex structure: therapeutic and diagnostic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

4-thio-deoxyuridylate-modified thrombin aptamer and its inhibitory effect on fibrin clot formation, platelet aggregation and thrombus growth on subendothelial matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Combinatorial synthesis of thrombin-binding aptamers containing iso-guanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Inhibition of High Affinity Basic Fibroblast Growth Factor Binding by Oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Ion selective folding of loop domains in a potent anti-HIV oligonucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA aptamers derived from HIV-1 RNase H inhibitors are strong anti-integrase agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Unique quadruplex structure and interaction of an RNA aptamer against bovine prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Anti-bovine prion protein RNA aptamer containing tandem GGA repeat interacts both with recombinant bovine prion protein and its beta isoform with high affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Antiproliferative activity of G-rich oligonucleotides correlates with protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-Quadruplex-based DNAzyme for colorimetric detection of cocaine: using magnetic nanoparticles as the separation and amplification element

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Multifunctional G-quadruplex aptamers and their application to protein detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Aptamer-based tumor-targeted drug delivery for photodynamic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A genome-inspired DNA ligand for the affinity capture of insulin and insulin-like growth factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

In vitro selection and characterization of RNA aptamers binding thyroxine hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Immobilized DNA switches as electronic sensors for picomolar detection of plasma proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Electrochemical aptasensor based on the dual-amplification of G-quadruplex horseradish peroxidase-mimicking DNAzyme and blocking reagent-horseradish peroxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Aptamer-DNAzyme hairpins for amplified biosensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Functional nucleic acid nanostructures and DNA machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure-based design of selective high-affinity telomeric quadruplex-binding ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A hitchhiker's guide to G-quadruplex ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplexes: targets in anticancer drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA and RNA quadruplex ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex recognition by bis-indole carboxamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Pyridyl-substituted corrole isomers: synthesis and their regulation to G-quadruplex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Small molecule-mediated inhibition of translation by targeting a native RNA G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

The role of G-quadruplex in RNA metabolism: involvement of FMRP and FMR2P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Crystallographic studies of quadruplex nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Selenium derivatization of nucleic acids for X-ray crystal-structure and function studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Method for direct discrimination of intra- and intermolecular hydrogen bonds, and characterization of the G(:A):G(:A):G(:A):G heptad, with scalar couplings across hydrogen bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Triplex and quadruplex DNA structures studied by electrospray mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Tetramolecular G-quadruplex formation pathways studied by electrospray mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Cyclo[n]pyrroles: size and site-specific binding to G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Study of binding affinity and selectivity of perylene and coronene derivatives towards duplex and quadruplex DNA by ESI-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Ligand binding to tetra-end-linked (TGGGGT)4 G-quadruplexes: an electrospray mass spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A non-empirical chromophoric interpretation of CD spectra of DNA G-quadruplex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Circular dichroism of quadruplex DNAs: applications to structure, cation effects and ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Kinetics and thermodynamics of G-quadruplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Supramolecular architectures generated by self-assembly of guanosine derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Guanosine hydrogen-bonded scaffolds: a new way to control the bottom-up realisation of well-defined nanoarchitectures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Molecular visualization of immunoglobulin switch region RNA/DNA complex by atomic force microscope

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Direct visualization of G-quadruplexes in DNA using atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A new DNA nanostructure, the G-wire, imaged by scanning probe microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Conformational switch of a functional nanowire based on the DNA G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Nanopatterning the surface with ordered supramolecular architectures of N(9)-alkylated guanines: STM reveals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Persistent, well-defined, monodisperse, pi-conjugated organic nanoparticles via G-quadruplex self-assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA nanomachines and nanostructures involving quadruplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Identification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Fluorescence-based melting assays for studying quadruplex ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

2-aminopurine as a probe for quadruplex loop structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Monitoring the temperature unfolding of G-quadruplexes by UV and circular dichroism spectroscopies and calorimetry techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Stability and kinetics of G-quadruplex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Analytical ultracentrifugation: sedimentation velocity and sedimentation equilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Sedimentation velocity ultracentrifugation analysis for hydrodynamic characterization of G-quadruplex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

DNA G-quartets in a 1.86 A resolution structure of an Oxytricha nova telomeric protein-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Selectivity in ligand recognition of G-quadruplex loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Fluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

An unusually stable G-quadruplex within the 5'-UTR of the MT3 matrix metalloproteinase mRNA represses translation in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

5'-UTR G-quadruplex structures acting as translational repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

PlasmodiumTelomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Targeting telomeres and telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

Stabilization and Structure of Telomeric and c-myc Region Intramolecular G-Quadruplexes: The Role of Central Cations and Small Planar Ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1CS15067G

21 January 2018

Identifiers

DOI

10.1039/C1CS15067G

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21789296%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference