Hepatitis B virus X gene and hepatocarcinogenesis. (Q37885837)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647825%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

review article

1 reference

title

Hepatitis B virus X gene and hepatocarcinogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647825%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

0 references

1 reference

1

1 reference

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3 February 2020

Caroline Lee

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647825%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

Sue-Ann Ng

series ordinal

1

1 reference

24 August 2017

Caroline Lee

series ordinal

2

1 reference

24 August 2017

publication date

8 June 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647825%20AND%20SRC:MED&resulttype=core&format=json

Journal of Gastroenterology

3 February 2020

published in

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3 February 2020

volume

46

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3 February 2020

issue

8

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3 February 2020

page(s)

974-990

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Primary liver cancer: worldwide incidence and trends

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Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

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Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

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Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1.

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Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis

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Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NF-kappa B.

21 January 2018

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Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells

21 January 2018

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21 January 2018

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Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

21 January 2018

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Detection of the hepatitis B virus X protein (HBx) antigen and anti-HBx antibodies in cases of human hepatocellular carcinoma

21 January 2018

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X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

21 January 2018

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

21 January 2018

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Proteomic analysis of liver tissue from HBx-transgenic mice at early stages of hepatocarcinogenesis.

21 January 2018

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Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis

21 January 2018

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The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

21 January 2018

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21 January 2018

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Early and frequent detection of HBxAg and/or anti-HBx in hepatitis B virus infection

21 January 2018

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The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication

21 January 2018

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21 January 2018

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21 January 2018

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Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor

21 January 2018

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The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway

21 January 2018

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Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.

21 January 2018

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Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

21 January 2018

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Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

21 January 2018

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HBx protein of hepatitis B virus activates Jak1-STAT signaling

21 January 2018

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Raf-1 and protein kinase B regulate cell survival through the activation of NF-kappaB in hepatitis B virus X-expressing cells

21 January 2018

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The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication

21 January 2018

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Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells.

21 January 2018

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21 January 2018

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21 January 2018

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Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis

21 January 2018

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Role of the HBx oncoprotein in carbonic anhydrase 9 induction

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Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2

21 January 2018

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Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level

21 January 2018

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Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase

21 January 2018

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The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines

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Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

21 January 2018

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21 January 2018

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p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

21 January 2018

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The hepatitis B virus X gene induces p53-mediated programmed cell death

21 January 2018

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Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection

21 January 2018

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Hepatitis B virus sensitizes hepatocytes to TRAIL-induced apoptosis through Bax.

21 January 2018

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Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting Bcl-xL expression

21 January 2018

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c-Fos is a mediator of the c-myc-induced apoptotic signaling in serum-deprived hepatoma cells via the p38 mitogen-activated protein kinase pathway

21 January 2018

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Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex

21 January 2018

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UVDDB p127-binding modulates activities and intracellular distribution of hepatitis B virus X protein

21 January 2018

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Role of the hepatitis B virus proteins in pro- and anti-apoptotic processes.

21 January 2018

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Apoptosis and viral hepatitis

21 January 2018

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Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

21 January 2018

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Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death

21 January 2018

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Involvement of mitochondrial permeability transition in hepatitis B virus replication

21 January 2018

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Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis.

21 January 2018

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HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70.

21 January 2018

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Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential

21 January 2018

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Hepatitis B virus integration, fragile sites, and hepatocarcinogenesis

21 January 2018

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Hepatitis B virus X protein inhibits nucleotide excision repair

21 January 2018

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Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

21 January 2018

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Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1.

21 January 2018

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Hepatitis B virus X protein induces hypermethylation of p16(INK4A) promoter via DNA methyltransferases in the early stage of HBV-associated hepatocarcinogenesis

21 January 2018

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Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16(INK4a) expression via DNA methylation

21 January 2018

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Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma

21 January 2018

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Sequential accumulation of the mutations in core promoter of hepatitis B virus is associated with the development of hepatocellular carcinoma in Qidong, China

21 January 2018

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Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection.

21 January 2018

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Specific mutations in the enhancer II/core promoter/precore regions of hepatitis B virus subgenotype C2 in Korean patients with hepatocellular carcinoma.

21 January 2018

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Biological impacts of "hot-spot" mutations of hepatitis B virus X proteins are genotype B and C differentiated

21 January 2018

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Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

21 January 2018

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Identification and characterization of a prevalent hepatitis B virus X protein mutant in Taiwanese patients with hepatocellular carcinoma

21 January 2018

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Deletion mutants of the hepatitis B virus X gene in human hepatocellular carcinoma

21 January 2018

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Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas

21 January 2018

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COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

21 January 2018

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A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function

21 January 2018

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Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.

21 January 2018

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Hot-spot mutations in hepatitis B virus X gene in hepatocellular carcinoma

21 January 2018

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Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients: comparative analysis of 40 full-length isolates

21 January 2018

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A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase

21 January 2018

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Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function.

21 January 2018

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Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0415-9

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Hepatitis B virus X protein (HBx) induces G2/M arrest and apoptosis through sustained activation of cyclin B1-CDK1 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Hepatitis B virus X protein overcomes the growth-inhibitory potential of retinoic acid by downregulating retinoic acid receptor-beta2 expression via DNA methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Hepatitis B virus X protein interferes with cellular DNA repair.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Telomerase activation in human hepatocarcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647825

12 December 2020

Stimulation of inducible nitric oxide by hepatitis B virus transactivator protein HBx requires MTA1 coregulator

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1074/JBC.M109.065987

Identifiers

DOI

10.1007/S00535-011-0415-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647825%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference