Exploring the genomes of cancer cells: progress and promise (Q37857590)

24 August 2017

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title

Exploring the genomes of cancer cells: progress and promise (English)

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24 August 2017

Michael R Stratton

1

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24 August 2017

language of work or name

English

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publication date

1 March 2011

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24 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

Science

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24 August 2017

volume

331

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24 August 2017

issue

6024

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24 August 2017

page(s)

1553-1558

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https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

24 August 2017

1 reference

21 January 2018

The Hallmarks of Cancer

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The impact of translocations and gene fusions on cancer causation

21 January 2018

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A census of human cancer genes

21 January 2018

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A census of amplified and overexpressed human cancer genes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

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A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy

21 January 2018

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Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

21 January 2018

1 reference

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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

21 January 2018

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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The genetic landscape of the childhood cancer medulloblastoma

21 January 2018

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High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

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A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

21 January 2018

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Mutation of GATA3 in human breast tumors

21 January 2018

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

21 January 2018

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The genomic landscapes of human breast and colorectal cancers

21 January 2018

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The consensus coding sequences of human breast and colorectal cancers

21 January 2018

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

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Colorectal cancer: mutations in a signalling pathway

21 January 2018

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Mutational analysis of the tyrosine kinome in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Diverse somatic mutation patterns and pathway alterations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

21 January 2018

1 reference

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Frequent mutation of BAP1 in metastasizing uveal melanomas

21 January 2018

1 reference

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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

21 January 2018

1 reference

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Target-enrichment strategies for next-generation sequencing

21 January 2018

1 reference

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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

21 January 2018

1 reference

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ARID1A mutations in endometriosis-associated ovarian carcinomas

21 January 2018

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Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

21 January 2018

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

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The mutation spectrum revealed by paired genome sequences from a lung cancer patient

21 January 2018

1 reference

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A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

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A small-cell lung cancer genome with complex signatures of tobacco exposure

21 January 2018

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

21 January 2018

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Recurring mutations found by sequencing an acute myeloid leukemia genome

21 January 2018

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DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

21 January 2018

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Mutator phenotype in cancer: origin and consequences

21 January 2018

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Linking somatic genetic alterations in cancer to therapeutics

21 January 2018

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Signatures of mutation and selection in the cancer genome

21 January 2018

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Lung cancer: intragenic ERBB2 kinase mutations in tumours

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

IDH1 and IDH2 mutations in gliomas

21 January 2018

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DNMT3A Mutations in Acute Myeloid Leukemia

21 January 2018

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What can we learn from the population incidence of cancer? Armitage and Doll revisited

21 January 2018

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Translation of the Philadelphia chromosome into therapy for CML.

21 January 2018

1 reference

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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

21 January 2018

1 reference

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Molecular predictors of response to trastuzumab and lapatinib in breast cancer.

21 January 2018

1 reference

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

1 reference

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Synthetic lethal approaches to breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Complex landscapes of somatic rearrangement in human breast cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

21 January 2018

1 reference

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Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 January 2018

1 reference

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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

21 January 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

21 January 2018

1 reference

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Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Genetic variegation of clonal architecture and propagating cells in leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

Development of personalized tumor biomarkers using massively parallel sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

International network of cancer genome projects

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1204040

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1204040

1 reference

24 August 2017

1 reference