Mechanisms and functional implications of intestinal barrier defects (Q37629444)

21 August 2017

1 reference

title

Mechanisms and functional implications of intestinal barrier defects (English)

1 reference

21 August 2017

Le Shen

1

1 reference

21 August 2017

Liping Su

series ordinal

2

1 reference

21 August 2017

Jerrold R Turner

series ordinal

3

1 reference

21 August 2017

4 November 2009

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21 August 2017

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21 August 2017

27

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21 August 2017

4

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21 August 2017

443-449

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T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Infliximab for induction and maintenance therapy for ulcerative colitis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Dedicated myosin light chain kinases with diverse cellular functions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Intestinal permeability in children with Crohn's disease and coeliac disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

The density of small tight junction pores varies among cell types and is increased by expression of claudin-2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

28 September 2017

Myosin minireview series

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Permeable junctional complexes. The movement of lanthanum across rabbit gallbladder and intestine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Permeability of the rat small intestinal epithelium along the villus-crypt axis: effects of glucose transport

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Permeability in Crohn's disease: altered barrier functions in healthy relatives?

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Intestinal permeability in patients with Crohn's disease and their healthy relatives

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Paracellular intestinal absorption of glucose, creatinine, and mannitol in normal animals: relation to body size

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Anaphylactic shock after retreatment with OKT3 monoclonal antibody

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Luminal nutrients alter tight-junction permeability in the rat jejunum: an in vivo perfusion model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Predicting relapse in Crohn's disease: a biopsychosocial model

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814011

Environmental stress-induced gastrointestinal permeability is mediated by endogenous glucocorticoids in the rat

3 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Sodium-glucose cotransport and epithelial permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Abnormal intestinal permeability predicts relapse in inactive Crohn disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Ultrastructural pathology of Crohn's disease: correlated transmission electron microscopy, scanning electron microscopy, and freeze fracture studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

A freeze fracture study of Crohn's disease of the terminal ileum: changes in epithelial tight junction organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Abnormal small intestinal permeability to sugars in patients with Crohn's disease of the terminal ileum and colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Reduction of morbidity and cytokine release in anti-CD3 MoAb-treated mice by corticosteroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Intestinal permeability and the prediction of relapse in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Effect of D-glucose on intestinal permeability and its passive absorption in human small intestine in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Physiological regulation of intestinal epithelial tight junctions as a consequence of Na(+)-coupled nutrient transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Discrimination of site-specific alterations in gastrointestinal permeability in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Intestinal permeability test as a predictor of clinical course in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897958

12 December 2020

Identifiers

DOI

10.1159/000233282

1 reference

release_xq5wle7mnnayjmks3xwdupmwhi

21 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xq5wle7mnnayjmks3xwdupmwhi

24 November 2022

mapped directly with Wikidata item

1 reference

21 August 2017

PubMed publication ID

19897958

1 reference