Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells (Q37621199)

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22 October 2019

title

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells (English)

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22 October 2019

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7 July 2024

author name string

O. Donzé

1

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7 July 2024

R. Jagus

2

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A. E. Koromilas

3

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J. W. Hershey

4

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N. Sonenberg

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English

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publication date

1 August 1995

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full work available at URL

22 October 2019

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7 July 2024

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7 July 2024

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7 July 2024

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10.1002/J.1460-2075.1995.TB00052.X

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7 July 2024

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22 October 2019

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14

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22 October 2019

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15

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22 October 2019

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3828-3834

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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

22 October 2019

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Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation

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Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

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The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties

23 August 2017

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The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

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Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases

23 August 2017

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Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA

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Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells

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23 August 2017

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Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell lines

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Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control

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Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

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12 December 2020

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The Interferon-Induced Double-Stranded RNA-Activated Human p68 Protein Kinase Potently Inhibits Protein Synthesis in Cultured Cells

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12 December 2020

10.1002/J.1460-2075.1995.TB00052.X

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22 October 2019

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22 October 2019

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