Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer. (Q37599935)

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8 March 2020

title

Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer (English)

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8 March 2020

8

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8 March 2020

Charles Rudin

13

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Trever G Bivona

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Eric A Collisson

1 reference

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Barry S Taylor

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8 March 2020

author name string

Luping Lin

1

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8 March 2020

Saurabh Asthana

2

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8 March 2020

Elton Chan

3

1 reference

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8 March 2020

Sourav Bandyopadhyay

4

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8 March 2020

Maria M Martins

5

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8 March 2020

Victor Olivas

6

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8 March 2020

Jenny Jiacheng Yan

7

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Mingxue Michelle Wang

9

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8 March 2020

David B Solit

11

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8 March 2020

Gideon Bollag

10

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language of work or name

English

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publication date

3 February 2014

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Proceedings of the National Academy of Sciences of the United States of America

8 March 2020

published in

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volume

111

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issue

7

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page(s)

E748-57

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Molecular characterization of acquired resistance to the BRAF inhibitor dabrafenib in a patient with BRAF-mutant non-small-cell lung cancer

8 March 2020

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Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

23 August 2017

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Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

23 August 2017

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

23 August 2017

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Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations

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AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

23 August 2017

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The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

23 August 2017

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

23 August 2017

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23 August 2017

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Rewired ERK-JNK signaling pathways in melanoma

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

23 August 2017

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23 August 2017

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23 August 2017

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A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib.

14 September 2017

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Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations.

1 September 2018

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1 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24550319

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1320956111

1 reference

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8 March 2020

0 references

1 reference

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8 March 2020

PubMed publication ID

24550319

1 reference