Valganciclovir in adult solid organ transplant recipients: pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements. (Q37570464)

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scientific article published on January 2009

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English	Valganciclovir in adult solid organ transplant recipients: pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements.	scientific article published on January 2009

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scholarly article

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4 February 2020

1 reference

Europe PubMed Central

Valganciclovir in adult solid organ transplant recipients: pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements (English)

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Europe PubMed Central

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4 February 2020

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

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pharmacodynamics

1 reference

based on heuristic

inferred from title

Laurent Arthur Decosterd

2

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Europe PubMed Central

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4 February 2020

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Nancy Perrottet

1

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4 February 2020

Pascal Meylan

3

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4 February 2020

Manuel Pascual

4

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4 February 2020

Jerome Biollaz

5

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4 February 2020

Thierry Buclin

6

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4 February 2020

language of work or name

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publication date

1 January 2009

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4 February 2020

Clinical Pharmacokinetics

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4 February 2020

48

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4 February 2020

6

1 reference

Europe PubMed Central

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4 February 2020

399-418

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19650679%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Human pharmacokinetics of the antiviral drug DHPG.

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Human pharmacokinetics and tolerance of oral ganciclovir

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Population differences in ganciclovir clearance as determined by nonlinear mixed-effects modelling

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Nonparametric expectation maximization population modeling of ganciclovir.

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Pharmacokinetics of oral ganciclovir alone and in combination with zidovudine, didanosine, and probenecid in HIV-infected subjects

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegaloviruses

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Effects of the nucleoside analog 2'-nor-2'-deoxyguanosine on human cytomegalovirus replication

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Activity of 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine in the treatment of cytomegalovirus pneumonia

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Ganciclovir sensitivity of cytomegalovirus at diagnosis and during treatment of cytomegalovirus pneumonia in marrow transplant recipients.

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Pharmacokinetic, safety, and antiviral profiles of oral ganciclovir in persons infected with human immunodeficiency virus: a phase I/II study. AIDS Clinical Trials Group, and Cytomegalovirus Cooperative Study Group

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Toxicity of 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Neurotoxicity related to valganciclovir in a child with impaired renal function: usefulness of therapeutic drug monitoring

1 reference

https://api.crossref.org/works/10.2165%2F00003088-200948060-00006

21 January 2018

Ganciclovir susceptibilities of cytomegalovirus (CMV) isolates from solid organ transplant recipients with CMV viremia after antiviral prophylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics and safety profile of oral ganciclovir combined with zalcitabine or stavudine in asymptomatic HIV- and CMV-seropositive patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An enantiospecific synthesis of the human cytomegalovirus antiviral agent [(R)-3-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-4- hydroxybutyl]phosphonic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seizures associated with ganciclovir therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral susceptibility testing of cytomegalovirus: criteria for detecting resistance to antivirals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir treatment of life- or sight-threatening cytomegalovirus infection: experience in 314 immunocompromised patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low plasma concentrations achieved with conventional schedules of administration of ganciclovir in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Basis of Prodrug Activation by Human Valacyclovirase, an -Amino Acid Ester Hydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychiatric Disturbances Associated with Ganciclovir Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir permeation of the human erythrocyte membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir hepatotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ganciclovir in pediatric renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS. An AIDS Clinical Trials Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of prophylactic ganciclovir on renal function and cyclosporine levels after heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of combinations of difluoromethylornithine (DFMO) and 9[(1,3-dihydroxy-2-propoxy) methyl]guanine (DHPG) on human cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of ganciclovir in patients with normal and impaired renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canadian society of transplantation consensus workshop on cytomegalovirus management in solid organ transplantation final report

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo activities of phosphate derivatives of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine against cytomegaloviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absolute bioavailability and dose proportionality of oral ganciclovir after ascending multiple doses in human immunodeficiency virus (HIV)-positive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral ganciclovir dosing in transplant recipients and dialysis patients based on renal function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2'-Nor-cGMP: a seco-cyclic nucleotide with powerful anti-DNA-viral activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ganciclovir in haematopoietic stem cell transplantation recipients with or without renal impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of valganciclovir during continuous renal replacement therapy in two lung transplant recipients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-emptive treatment with oral valganciclovir in management of CMV infection after cardiac transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral ganciclovir in pediatric transplant recipients: a pharmacokinetic study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valganciclovir as treatment for cytomegalovirus disease in solid organ transplant recipients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective assessment of valganciclovir for the treatment of cytomegalovirus infection and disease in transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High dose oral ganciclovir treatment for cytomegalovirus retinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of mycophenolate mofetil and intravenous ganciclovir alone and in combination in renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring plasma levels of ganciclovir in AIDS patients receiving oral ganciclovir as maintenance therapy for CMV retinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral Valganciclovir Is Noninferior to Intravenous Ganciclovir for the Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral activity and mechanism of action of ganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir use during mild renal failure in heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir-induced encephalopathy in a bone marrow transplant recipient

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir absolute bioavailability and steady-state pharmacokinetics after oral administration of two 3000-mg/d dosing regimens in human immunodeficiency virus— and cytomegalovirus-seropositive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system side effects of ganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutropenia in allogeneic marrow transplant recipients receiving ganciclovir for prevention of cytomegalovirus disease: risk factors and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ganciclovir after oral valganciclovir versus intravenous ganciclovir in allogeneic stem cell transplant patients with graft-versus-host disease of the gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-emptive therapy against cytomegalovirus (CMV) disease guided by CMV antigenemia assay after allogeneic hematopoietic stem cell transplantation: a single-center experience in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of ganciclovir to treat serious cytomegalovirus infections in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of preemptive anti-CMV therapy with valganciclovir after kidney transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishing pharmacokinetic bioequivalence of valganciclovir oral solution versus the tablet formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of cytomegalovirus disease with valganciclovir in renal transplant recipients: a single center experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir treatment of cytomegalovirus disease in transplant recipients and other immunocompromised hosts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial experience with oral valganciclovir for pre-emptive cytomegalovirus therapy after lung transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of high-dose oral ganciclovir on didanosine disposition in human immunodeficiency virus (HIV)-positive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose pharmacokinetics of valganciclovir in HIV- and CMV-seropositive subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valganciclovir preemptive therapy for the prevention of cytomegalovirus disease in high-risk seropositive solid-organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valganciclovir: a review of its use in the management of CMV infection and disease in immunocompromised patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir therapy for cytomegalovirus infections in recipients of bone marrow transplants and other immunosuppressed patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible ganciclovir-induced hepatotoxicity in patients with AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of valganciclovir administered as preemptive therapy for cytomegalovirus disease in liver transplant recipients: impact on viral load and late-onset cytomegalovirus disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valganciclovir as preemptive therapy for cytomegalovirus in cytomegalovirus-seronegative liver transplant recipients of cytomegalovirus-seropositive donor allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the pharmacokinetics, antiviral activity, and tolerability of oral ganciclovir for CMV prophylaxis in marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylactic oral ganciclovir after renal transplantation-dosing and pharmacokinetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of clinical isolates of human cytomegalovirus to 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of valganciclovir and ganciclovir following multiple oral dosages of valganciclovir in HIV- and CMV-seropositive volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir pharmacokinetics and cytokine dynamics in renal transplant recipients with cytomegalovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of cytomegalovirus infections with ganciclovir in kidney transplant recipients. Clinical and pharmacokinetic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection in solid-organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of aciclovir and ganciclovir in human plasma by liquid chromatography-spectrofluorimetric detection and stability studies in blood samples.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of valganciclovir as induction therapy for cytomegalovirus retinitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurologic side-effects of ganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir-induced psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir in solid organ transplant recipients: is there a role for clinical pharmacokinetic monitoring?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytomegalovirus prophylaxis with valganciclovir in African-American renal allograft recipients based on donor/recipient serostatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dosing of intravenous ganciclovir for the prophylaxis and treatment of cytomegalovirus infection in solid organ transplant recipients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of valganciclovir and ganciclovir in renal impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of Cytomegalovirus Infection or Disease in Solid Organ Transplant Recipients with Valganciclovir

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral valganciclovir leads to higher exposure to ganciclovir than intravenous ganciclovir in patients following allogeneic stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics in the 21st century. Does the evidence support definitive outcomes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganciclovir: an update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19650679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200948060-00006

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19650679%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19650679%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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