20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site (Q37444386)

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scientific article published on 17 September 2009

Language	Label	Description	Also known as
English	20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site	scientific article published on 17 September 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Yuenmu Chen

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

John R Falck

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Venugopal R Tuniki

3

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Europe PubMed Central

PMC publication ID

20 August 2017

William B Campbell

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

17 September 2009

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Europe PubMed Central

PMC publication ID

20 August 2017

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

PMC publication ID

20 August 2017

331

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Europe PubMed Central

PMC publication ID

20 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1137-1145

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

1 reference

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23 August 2017

Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of beta-endorphin and met-enkephalin in the rat ventrolateral periaqueductal gray.

1 reference

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23 August 2017

Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.

1 reference

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23 August 2017

Roles of epoxyeicosatrienoic acids in vascular regulation and cardiac preconditioning

1 reference

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23 August 2017

Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors

1 reference

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23 August 2017

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

1 reference

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23 August 2017

Action of epoxyeicosatrienoic acids on cellular function

1 reference

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23 August 2017

The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids, and soluble epoxide hydrolase

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23 August 2017

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

1 reference

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23 August 2017

The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands

1 reference

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23 August 2017

Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis

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23 August 2017

Binding of cytochrome P450 monooxygenase and lipoxygenase pathway products by heart fatty acid-binding protein

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23 August 2017

Cytochrome P450 2C is an EDHF synthase in coronary arteries

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23 August 2017

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

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Potent urea and carbamate inhibitors of soluble epoxide hydrolases

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23 August 2017

Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors

1 reference

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Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid

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23 August 2017

Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone

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14 September 2017

Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.

1 reference

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28 September 2017

Post-receptor signal transduction and regulation of 14(R),15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells

1 reference

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Synthesis and binding affinity of an iodinated juvenile hormone.

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26 June 2018

Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid

1 reference

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2 September 2018

Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids

1 reference

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11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression

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2 September 2018

14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries

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Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation

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Evidence for a membrane site of action for 14,15-EET on expression of aromatase in vascular smooth muscle

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2 September 2018

14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries

1 reference

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The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells.

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Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids

1 reference

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Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein.

1 reference

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14(R),15(S)-epoxyeicosatrienoic acid (14(R),15(S)-EET) receptor in guinea pig mononuclear cell membranes.

1 reference

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Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats

1 reference

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Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: characterization of selective inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19762546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19762546

12 December 2020

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inferred from PubMed ID database lookup

Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19762546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19762546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/JPET.109.157818

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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