An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain. (Q37427453)

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28 March 2020

title

An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain (English)

1 reference

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28 March 2020

8

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28 March 2020

author name string

Yanting Yin

1

1 reference

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X Edward Zhou

2

1 reference

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28 March 2020

Li Hou

3

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Li-Hua Zhao

4

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28 March 2020

Bo Liu

5

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Gaihong Wang

6

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Yi Jiang

7

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H Eric Xu

9

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publication date

22 November 2016

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28 March 2020

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volume

2

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page(s)

16042

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Creative Commons Attribution 4.0 International

28 March 2020

copyright license

start time

22 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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23 August 2017

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Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas

23 August 2017

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Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

23 August 2017

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The major determinant of exendin-4/glucagon-like peptide 1 differential affinity at the rat glucagon-like peptide 1 receptor N-terminal domain is a hydrogen bond from SER-32 of exendin-4.

6 September 2017

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Possible endogenous agonist mechanism for the activation of secretin family G protein-coupled receptors

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Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues

14 September 2017

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Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

14 September 2017

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Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

28 September 2017

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A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification.

28 September 2017

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Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients.

26 June 2018

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Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

26 June 2018

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Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.

26 June 2018

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Development of a cysteine-deprived and C-terminally truncated GLP-1 receptor.

26 June 2018

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Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes

2 September 2018

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Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2.

2 September 2018

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Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.

2 September 2018

1 reference

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Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

2 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FCELLDISC.2016.42

7 January 2021

Class-B GPCR activation: is ligand helix-capping the key?

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https://api.crossref.org/works/10.1038%2FCELLDISC.2016.42

7 January 2021

High potency antagonists of the pancreatic glucagon-like peptide-1 receptor

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https://api.crossref.org/works/10.1038%2FCELLDISC.2016.42

7 January 2021

Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method

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7 January 2021

Identifiers

DOI

10.1038/CELLDISC.2016.42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27917297%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

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28 March 2020

PubMed publication ID

27917297

1 reference