Defective signal transduction by the CD2 molecule in immature T-cell receptor/CD3- thymocytes (Q37207106)

18 August 2017

Defective signal transduction by the CD2 molecule in immature T-cell receptor/CD3- thymocytes (English)

1 reference

18 August 2017

0 references

lymphocyte activation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

20 September 2022

5

June CH

1 reference

18 August 2017

L. A. Turka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

20 September 2022

M. C. Fletcher

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

20 September 2022

N. Craighead

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

20 September 2022

C. B. Thompson

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

20 September 2022

language of work or name

English

0 references

publication date

1 September 1992

1 reference

PMC publication ID

49989

18 August 2017

15 September 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1382296

full work available at URL

20 September 2022

https://europepmc.org/articles/PMC49989

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

https://europepmc.org/articles/PMC49989?pdf=render

20 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1382296

Proceedings of the National Academy of Sciences of the United States of America

20 September 2022

published in

1 reference

18 August 2017

89

1 reference

18 August 2017

18

1 reference

18 August 2017

8706-8710

1 reference

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Selection and characterization of T-cell variants lacking molecules involved in T-cell activation (T3 T-cell receptor, T44, and T11): analysis of the functional relationship among different pathways of activation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Selective inhibition of interleukin 2 gene function following thymocyte antigen/major histocompatibility complex receptor crosslinking: possible thymic selection mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Developmental biology of T cell receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Do CD2 and CD3-TCR T-cell activation pathways function independently?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Human thymocyte maturation in vitro: a flow cytometric analysis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Unusual expression of CD2 in sheep: implications for T cell interactions

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

The T11 (CD2) molecule is functionally linked to the T3/Ti T cell receptor in the majority of T cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Stimulation via CD3-Ti but not CD2 induces rapid tyrosine phosphorylation of a 68-kDa protein in the human Jurkat T cell line

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

CD2 can mediate TCR/CD3-independent T cell activation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=49989

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry

26 June 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Only dull CD3+ thymocytes bind to thymic epithelial cells. The binding is elicited by both CD2/LFA-3 and LFA-1/ICAM-1 interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Factor requirements for activation and proliferation steps of human CD2+CD3-CD4-CD8- early thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Activation of human thymocytes via the 50KD T11 sheep erythrocyte binding protein induces the expression of interleukin 2 receptors on both T3+ and T3- populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Signal transduction via CD4, CD8, and CD28 in mature and immature thymocytes. Implications for thymic selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

CD28 is an inducible T cell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

The effects of anti-CD2 antibodies on the differentiation of mouse thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Expression and ontogeny of murine CD2

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Expression and function of CD2 during murine thymocyte ontogeny

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/1382296

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.18.8706

1 reference

18 August 2017

0 references

1 reference

PMC publication ID

49989

18 August 2017

1 reference

PMC publication ID

49989