Transmembrane segment peptides can disrupt cholecystokinin receptor oligomerization without affecting receptor function (Q36978929)

17 August 2017

Transmembrane segment peptides can disrupt cholecystokinin receptor oligomerization without affecting receptor function (English)

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17 August 2017

transmembrane protein

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1 reference

Kaleeckal G Harikumar

1

1 reference

17 August 2017

Maoqing Dong

2

1 reference

17 August 2017

Zhijie Cheng

3

1 reference

17 August 2017

Delia I Pinon

4

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17 August 2017

Terry P Lybrand

5

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17 August 2017

Laurence J Miller

6

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17 August 2017

language of work or name

English

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publication date

1 December 2006

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17 August 2017

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17 August 2017

45

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17 August 2017

49

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17 August 2017

14706-14716

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Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

29 September 2017

1 reference

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The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics.

29 September 2017

1 reference

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Differential effects of modification of membrane cholesterol and sphingolipids on the conformation, function, and trafficking of the G protein-coupled cholecystokinin receptor

29 September 2017

1 reference

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Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Monitoring the formation of dynamic G-protein-coupled receptor-protein complexes in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

G protein-coupled receptor dimerization: function and ligand pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

The G protein-coupled receptor rhodopsin in the native membrane

29 September 2017

1 reference

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Minireview: Diversity and complexity of signaling through peptidergic G protein-coupled receptors

29 September 2017

1 reference

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Identification of amino acid residues crucial for chemokine receptor dimerization.

29 September 2017

1 reference

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Roles of G-protein-coupled receptor dimerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Dimerization of G-protein-coupled receptors: roles in signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein

29 September 2017

1 reference

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Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

29 September 2017

1 reference

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Oligomerization of opioid receptors

29 September 2017

1 reference

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Agonist-dependent dissociation of oligomeric complexes of G protein-coupled cholecystokinin receptors demonstrated in living cells using bioluminescence resonance energy transfer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Protein-protein interactions at G-protein-coupled receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Dimerization and domain swapping in G-protein-coupled receptors: a computational study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Crystal structure of rhodopsin: A G protein-coupled receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Functional significance of oligomerization of G-protein-coupled receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

A transmembrane helix dimer: structure and implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Reduced surface: an efficient way to compute molecular surfaces

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Relationship between native and recombinant cholecystokinin receptors: role of differential glycosylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

A new generation of Ca2+ indicators with greatly improved fluorescence properties

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Sequence specificity in the dimerization of transmembrane alpha-helices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Structural and functional aspects of G protein-coupled receptor oligomerization

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Use of N,O-bis-Fmoc-d-Tyr-ONSu for introduction of an oxidative iodination site into cholecystokinin family peptides

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Heterodimerization of Type A and B Cholecystokinin Receptors Enhance Signaling and Promote Cell Growth

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Structural models for dimerization of G-protein coupled receptors: the opioid receptor homodimers.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Refinement of the conformation of a critical region of charge-charge interaction between cholecystokinin and its receptor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Environment and mobility of a series of fluorescent reporters at the amino terminus of structurally related peptide agonists and antagonists bound to the cholecystokinin receptor

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Additional observations on cholecystokinin and the vasoactive intestinal polypeptide

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585497

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method

4 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

Domain swapping in G-protein coupled receptor dimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

Constitutive formation of oligomeric complexes between family B G protein-coupled vasoactive intestinal polypeptide and secretin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

Lipid-facing correlated mutations and dimerization in G-protein coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17144663

12 December 2020

Identifiers

DOI

10.1021/BI061107N

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

17144663

1 reference