Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve (Q36943422)

17 August 2017

Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve (English)

1 reference

17 August 2017

Zhilin Qu

1

1 reference

17 August 2017

Lai-Hua Xie

2

1 reference

17 August 2017

Riccardo Olcese

3

1 reference

17 August 2017

Hrayr S Karagueuzian

4

1 reference

17 August 2017

Peng-Sheng Chen

5

1 reference

17 August 2017

Alan Garfinkel

6

1 reference

17 August 2017

James N Weiss

7

1 reference

17 August 2017

25 April 2013

1 reference

17 August 2017

Cardiovascular Research

1 reference

17 August 2017

99

1 reference

17 August 2017

1

1 reference

17 August 2017

6-15

1 reference

Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Synchronization of early afterdepolarizations and arrhythmogenesis in heterogeneous cardiac tissue models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Intracellular calcium dynamics, shortened action potential duration, and late-phase 3 early afterdepolarization in Langendorff-perfused rabbit ventricles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Arrhythmogenic consequences of myofibroblast-myocyte coupling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Irregularly Appearing Early Afterdepolarizations in Cardiac Myocytes: Random Fluctuations or Dynamical Chaos?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Cardiac sodium channelopathies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

A short, biased history of triggered activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

The congenital long QT syndromes from genotype to phenotype: clinical implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Molecular and cellular mechanisms of cardiac arrhythmias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Pause induced early afterdepolarizations in the long QT syndrome: a simulation study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Fast inactivation causes rectification of the IKr channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

The clinical relevance of afterdepolarizations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Applications of Hodgkin-Huxley equations to excitable tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Voltage-dependent modulation of Ca channel current in heart cells by Bay K8644.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Triggered activity in the heart: cellular mechanisms of early after-depolarizations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Cellular mechanisms of early afterdepolarizations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Action potentials, afterpotentials, and arrhythmias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Early afterdepolarizations and cardiac arrhythmias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Magnesium suppression of early afterdepolarizations and ventricular tachyarrhythmias induced by cesium in dogs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Cellular basis of ventricular arrhythmias and abnormal automaticity in heart failure.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Direct measurement of L-type Ca2+ window current in heart cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Ionic mechanisms of electrophysiological properties and repolarization abnormalities in rabbit Purkinje fibers

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Bifurcation and chaos in a model of cardiac early afterdepolarizations

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Contribution of L-type Ca2+ channels to early afterdepolarizations induced by I Kr and I Ks channel suppression in guinea pig ventricular myocytes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3687754

Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FCVR%2FCVT104

Functional consequences of elimination of i(to,f) and i(to,s): early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Transmural action potential and ionic current remodeling in ventricles of failing canine hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Reconstruction of the repolarization process in cardiac Purkinje fibres based on voltage clamp measurements of membrane current

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Effects of pacing on triggered activity induced by early afterdepolarizations

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Quinidine-induced action potential prolongation, early afterdepolarizations, and triggered activity in canine Purkinje fibers. Effects of stimulation rate, potassium, and magnesium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Taking the "idio" out of "idiosyncratic": predicting torsades de pointes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

L-type calcium current reactivation contributes to arrhythmogenesis associated with action potential triangulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived from transgenic LQT1 and LQT2 rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/23619423

12 December 2020

Identifiers

DOI

10.1093/CVR/CVT104

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23619423

1 reference