Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics (Q36929572)

17 August 2017

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title

Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics (English)

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17 August 2017

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3

John L Markley

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17 August 2017

1

George N Phillips

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17 August 2017

7

Craig A Bingman

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17 August 2017

2

Brian G Fox

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17 August 2017

Brian F Volkman

4

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17 August 2017

Euiyoung Bae

5

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17 August 2017

Eduard Bitto

6

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17 August 2017

Ronnie O Frederick

8

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17 August 2017

Jason G McCoy

9

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17 August 2017

Betsy L Lytle

10

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17 August 2017

Brad S Pierce

11

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17 August 2017

Jikui Song

12

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17 August 2017

Simon N Twigger

13

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17 August 2017

language of work or name

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6 September 2007

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Journal of Structural and Functional Genomics

17 August 2017

published in

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17 August 2017

volume

8

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17 August 2017

issue

2-3

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17 August 2017

page(s)

73-84

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Magnetic resonance spectroscopy

17 August 2017

cites work

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Crossref

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Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis

21 January 2018

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Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients

21 January 2018

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12 December 2020

The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a

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12 December 2020

Characteristics of the cysteinesulfinate-forming enzyme system in rat liver

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12 December 2020

Dynein and dynein-related genes

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12 December 2020

Secretagogin is a new neuroendocrine marker in the human prostate

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12 December 2020

A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells.

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12 December 2020

Human pancreatic RNase1-human epidermal growth factor fusion: an entirely human 'immunotoxin analog' with cytotoxic properties against squamous cell carcinomas

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12 December 2020

Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine

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12 December 2020

Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A

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12 December 2020

Production in two-liter beverage bottles of proteins for NMR structure determination labeled with either 15N- or 13C-15N.

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Phosphomannomutase deficiency: the molecular basis of the classical Jaeken syndrome (CDGS type Ia)

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12 December 2020

Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene

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12 December 2020

Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Probabilistic approach to determining unbiased random-coil carbon-13 chemical shift values from the protein chemical shift database

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Ribonuclease A variants with potent cytotoxic activity

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12 December 2020

Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The 2-His-1-carboxylate facial triad: a versatile platform for dioxygen activation by mononuclear non-heme iron(II) enzymes.

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Kinetic properties and tissular distribution of mammalian phosphomannomutase isozymes

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

THE ENZYMATIC OXIDATION OF CYSTEINE TO CYSTEINESULFINATE IN RAT LIVER

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https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

SOMoRe: a multi-dimensional search and optimization approach to molecular replacement

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Functional analysis of pyrimidine 5'-nucleotidase mutants causing nonspherocytic hemolytic anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Cell-free protein production and labeling protocol for NMR-based structural proteomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The cytotoxicity of a conjugate composed of human epidermal growth factor and eosinophil cationic protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Cerebral expression and serum detectability of secretagogin, a recently cloned EF-hand Ca(2+)-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Pyrimidine 5' nucleotidase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

New clinical phenotype of branched-chain acyl-CoA oxidation defect

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Canavan disease: diagnosis and molecular analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Wheat germ cell-free platform for eukaryotic protein production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A deletion-insertion mutation in the phosphomannomutase 2 gene in an African American patient with congenital disorders of glycosylation-Ia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Biochemistry and molecular biology of Canavan disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Expression, purification, and kinetic characterization of recombinant rat cysteine dioxygenase, a non-heme metalloenzyme necessary for regulation of cellular cysteine levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Geometric and electronic structure/function correlations in non-heme iron enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Crystal structure of mammalian cysteine dioxygenase. A novel mononuclear iron center for cysteine thiol oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Pyrimidine nucleotidases from human erythrocyte possess phosphotransferase activities specific for pyrimidine nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Ribonuclease A can be transformed into a dimeric ribonuclease with antitumor activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Characteristics of a pyrimidine-specific 5'-nucleotidase in human erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Free radical catalysis by galactose oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A probabilistic approach to protein backbone tracing in electron density maps.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Enhanced activity of pyrimidine 5'-nucleotidase in rat red blood cells during erythropoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein fromHomo sapiens

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Cystein oxygenase. II. Studies on the mechanism of the reaction with 18oxygen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

N-acetylaspartate in neuropsychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Ethylmalonic encephalopathy is caused by mutations in ETHE1, a gene encoding a mitochondrial matrix protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A novel genetic system to isolate a dominant negative effector on DNA-binding activity of Oct-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The carbohydrate-deficient glycoprotein syndrome. A new inherited multisystemic disease with severe nervous system involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The roadblock light chain binds a novel region of the cytoplasmic Dynein intermediate chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Compensating effects on the cytotoxicity of ribonuclease A variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Structure of an ETHE1-like protein from Arabidopsis thaliana

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Secretagogin is a novel marker for neuroendocrine differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A cholesterol-lowering gene maps to chromosome 13q.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Gene therapy progress and prospects: viral trafficking during infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Cytotoxicity of human RNase-based immunotoxins requires cytosolic access and resistance to ribonuclease inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Biochemistry of sulfur-containing amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The virtuoso of versatility: POU proteins that flex to fit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Proteomics as a Tool for Discovery: Proteins Implicated in Alzheimer's Disease are Highly Expressed in Normal Pancreatic Islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Project management system for structural and functional proteomics: Sesame

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A new syndrome with ethylmalonic aciduria and normal fatty acid oxidation in fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Structure of Leishmania mexicana Phosphomannomutase Highlights Similarities with Human Isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Anti-angiogenic effect of an insertional fusion protein of human basic fibroblast growth factor and ribonuclease-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Non-heme iron enzymes: contrasts to heme catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Structure and mechanism of mouse cysteine dioxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Tandemization endows bovine pancreatic ribonuclease with cytotoxic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Solution structure of isoform 1 of Roadblock/LC7, a light chain in the dynein complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Characterization of human aspartoacylase: the brain enzyme responsible for Canavan disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

ETHE1 mutations are specific to ethylmalonic encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Insertional-fusion of basic fibroblast growth factor endowed ribonuclease 1 with enhanced cytotoxicity by steric blockade of inhibitor interaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

High efficiency single step production of expression plasmids from cDNA clones using the Flexi Vector cloning system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Variations of the 2-His-1-carboxylate theme in mononuclear non-heme FeII oxygenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

The LC7 light chains of Chlamydomonas flagellar dyneins interact with components required for both motor assembly and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Association and linkage of atopic dermatitis with chromosome 13q12-14 and 5q31-33 markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Lack of homozygotes for the most frequent disease allele in carbohydrate-deficient glycoprotein syndrome type 1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Action of Ribonuclease on Certain Ascites Tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Evaluation and modification of an assay procedure for cysteine dioxygenase activity: high-performance liquid chromatography method for measurement of cysteine sulfinate and demonstration of physiological relevance of cysteine dioxygenase activity in

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

KFERQ sequence in ribonuclease A-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

CDD: a Conserved Domain Database for protein classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Cytostatic and cytotoxic effects of Pannon (P-30 Protein), a novel anticancer agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Identification of cytidine diphosphodiesters in erythrocytes from a patient with pyrimidine nucleotidase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Lead poisoning: association with hemolytic anemia, basophilic stippling, erythrocyte pyrimidine 5'-nucleotidase deficiency, and intraerythrocytic accumulation of pyrimidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Hereditary pyrimidine 5'-nucleotidase deficiency: from genetics to clinical manifestations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Structure of aspartoacylase, the brain enzyme impaired in Canavan disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Carbohydrate-deficient glycoprotein syndrome type 1A: expression and characterisation of wild type and mutant PMM2 in E. coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Plasma cysteine and sulphate levels in patients with motor neurone, Parkinson's and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Inhibition of cell growth by a fused protein of human ribonuclease 1 and human basic fibroblast growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A tyrosine-derived free radical in apogalactose oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Endowing human pancreatic ribonuclease with toxicity for cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Action of Ribonuclease on Two Solid Tumours in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Specificity of amino acid acylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Hereditary hemolytic anemia with human erythrocyte pyrimidine 5'-nucleotidase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

Epidermal growth factor receptor-dependent cytotoxicity for human squamous carcinoma cell lines of a conjugate composed of human EGF and RNase 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17786587

12 December 2020

10.1007/S10969-007-9023-6

Identifiers

DOI

1 reference

17 August 2017

1 reference