Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2. (Q36859278)

16 August 2017

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2. (English)

1 reference

16 August 2017

10

Danny Reinberg

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Steven Gamblin

12

object named as

Steven J Gamblin

1 reference

16 August 2017

Jon R Wilson

11

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author name string

Neil Justin

1

1 reference

16 August 2017

Ying Zhang

2

1 reference

16 August 2017

Cataldo Tarricone

3

1 reference

16 August 2017

Stephen R Martin

4

1 reference

16 August 2017

Shuyang Chen

5

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16 August 2017

Elizabeth Underwood

6

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16 August 2017

Valeria De Marco

7

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16 August 2017

Lesley F Haire

8

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16 August 2017

Philip A Walker

9

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16 August 2017

language of work or name

English

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publication date

28 April 2016

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16 August 2017

Nature Communications

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16 August 2017

7

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16 August 2017

11316

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Creative Commons Attribution 4.0 International

16 August 2017

start time

28 April 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Strategy for "detoxification" of a cancer-derived histone mutant based on mapping its interaction with the methyltransferase PRC2

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Chromatin repressive complexes in stem cells, development, and cancer

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Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

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PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells.

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Promiscuous RNA binding by Polycomb repressive complex 2.

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Receptor binding by a ferret-transmissible H5 avian influenza virus

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The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

29 September 2017

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Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

29 September 2017

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An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting

29 September 2017

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Molecular architecture of human polycomb repressive complex 2

29 September 2017

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

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Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z)12 through Partially Overlapping Binding Sites

29 September 2017

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Histone methylation by PRC2 is inhibited by active chromatin marks

29 September 2017

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The Polycomb complex PRC2 and its mark in life

29 September 2017

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Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

29 September 2017

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Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies

29 September 2017

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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

29 September 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

29 September 2017

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29 September 2017

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Role of the polycomb protein EED in the propagation of repressive histone marks

29 September 2017

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Mechanisms of polycomb gene silencing: knowns and unknowns

29 September 2017

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AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

29 September 2017

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Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

29 September 2017

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Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

29 September 2017

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The complex language of chromatin regulation during transcription

29 September 2017

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

29 September 2017

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The SET-domain protein superfamily: protein lysine methyltransferases

29 September 2017

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29 September 2017

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29 September 2017

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Refinement of macromolecular structures by the maximum-likelihood method

29 September 2017

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29 September 2017

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29 September 2017

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Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase

29 September 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

29 September 2017

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Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation

29 September 2017

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Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS11316

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS11316

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

27121947

1 reference