Aberrant lipid metabolism: an emerging diagnostic and therapeutic target in ovarian cancer. (Q36820509)

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28 February 2020

title

Aberrant lipid metabolism: an emerging diagnostic and therapeutic target in ovarian cancer (English)

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28 February 2020

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3

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28 February 2020

author name string

Carmen E Pyragius

series ordinal

1

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28 February 2020

Maria Fuller

series ordinal

2

1 reference

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28 February 2020

Martin K Oehler

series ordinal

4

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28 February 2020

language of work or name

English

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publication date

10 April 2013

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International Journal of Molecular Sciences

28 February 2020

published in

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28 February 2020

volume

14

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28 February 2020

issue

4

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28 February 2020

page(s)

7742-7756

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Creative Commons Attribution 4.0 International

28 February 2020

copyright license

start time

10 April 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells.

29 September 2017

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

29 September 2017

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Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance

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Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells

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29 September 2017

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Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA carboxylase and impairs proliferation in cancer cells: role of AMPK

29 September 2017

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Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6

29 September 2017

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Sp-1 and c-Myc mediate lysophosphatidic acid-induced expression of vascular endothelial growth factor in ovarian cancer cells via a hypoxia-inducible factor-1-independent mechanism

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29 September 2017

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Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane

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Inhibition of lysophosphatidic acid receptor-2 expression by RNA interference decreases lysophosphatidic acid-induced urokinase plasminogen activator activation, cell invasion, and migration in ovarian cancer SKOV-3 cells

29 September 2017

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29 September 2017

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29 September 2017

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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

29 September 2017

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Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer

29 September 2017

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Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells

29 September 2017

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Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.

29 September 2017

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29 September 2017

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GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells

29 September 2017

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29 September 2017

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Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family

29 September 2017

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Killing tumours by ceramide-induced apoptosis: a critique of available drugs

29 September 2017

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Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

29 September 2017

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Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

29 September 2017

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Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

29 September 2017

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

29 September 2017

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Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor

29 September 2017

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Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis, and the NF-kappaB signal pathway

29 September 2017

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Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells

29 September 2017

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Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer

29 September 2017

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Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2.

29 September 2017

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Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

29 September 2017

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29 September 2017

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Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival

29 September 2017

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29 September 2017

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Dietary factors and the risk of epithelial ovarian cancer.

29 September 2017

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Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta.

29 September 2017

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Low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio predicts lipid-rich coronary plaque in patients with coronary artery disease--integrated-backscatter intravascular ultrasound study

27 June 2018

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A case-control study of diet and the risk of ovarian cancer

5 September 2018

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Lysophospholipids are potential biomarkers of ovarian cancer

5 September 2018

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Growth-regulated oncogene-1 expression is associated with angiogenesis and lymph node metastasis in human oral cancer

5 September 2018

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Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression

5 September 2018

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Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

5 September 2018

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Lysophosphatidic acid induces focal adhesion assembly through Rho/Rho-associated kinase pathway in human ovarian cancer cells

5 September 2018

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Plasma lysophosphatidic acid concentration and ovarian cancer

5 September 2018

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Lysophosphatidic acid promotes matrix metalloproteinase (MMP) activation and MMP-dependent invasion in ovarian cancer cells.

5 September 2018

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Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase.

5 September 2018

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Serum Autotaxin is not a Useful Biomarker for Ovarian Cancer

5 September 2018

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12 December 2020

Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Phospholipid metabolism in cancer cells monitored by 31P NMR spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Sulfatides in ovarian tumors: clinicopathological correlates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Dietary fat intake and risk of epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Blockade of fatty acid synthase induces ubiquitination and degradation of phosphoinositide-3-kinase signaling proteins in ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Prospective study of diet and ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Pleiotropic effects of CXC chemokines in gastric carcinoma: differences in CXCL8 and CXCL1 expression between diffuse and intestinal types of gastric carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23574936

12 December 2020

Identifiers

DOI

10.3390/IJMS14047742

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23574936%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23574936%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

23574936

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23574936%20AND%20SRC:MED&resulttype=core&format=json