Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis (Q36699754)

15 August 2017

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis (English)

1 reference

Leticia Quintanilla-Martinez

15 August 2017

1 reference

7

Leticia Quintanilla-Martinez

0 references

Andreas Gewies

Andreas Gewies

8

0 references

Jürgen Ruland

Jürgen Ruland

9

0 references

Werner Müller

Werner Müller

6

0 references

Klaus Rajewsky

Klaus Rajewsky

10

0 references

Ursula Zimber-Strobl

11

Ursula Zimber-Strobl

1 reference

15 August 2017

5

Lothar J Strobl

1 reference

15 August 2017

Cornelia Hömig-Hölzel

1

1 reference

15 August 2017

Caroline Hojer

2

1 reference

15 August 2017

Julia Rastelli

3

1 reference

15 August 2017

Stefano Casola

4

1 reference

15 August 2017

language of work or name

English

0 references

publication date

19 May 2008

1 reference

Journal of Experimental Medicine

15 August 2017

1 reference

15 August 2017

205

1 reference

15 August 2017

6

1 reference

15 August 2017

1317-1329

1 reference

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

A fourth IkappaB protein within the NF-kappaB signaling module

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Circuitry of nuclear factor kappaB signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

The role of the CD40 pathway in the pathogenesis and treatment of cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

CD40 regulates the processing of NF-kappaB2 p100 to p52

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

CD40 ligand (CD154) and tumour necrosis factor-related apoptosis inducing ligand (Apo-2L) in haematological malignancies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Generalized lacZ expression with the ROSA26 Cre reporter strain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated prot

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

B lymphocyte-specific, Cre-mediated mutagenesis in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Targeted oncogene activation by site-specific recombination in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Bethesda proposals for classification of lymphoid neoplasms in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2413030

Constitutive activation of the CD40 pathway promotes cell transformation and neoplastic growth

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

CD40 ligation in vivo induces bystander proliferation of memory phenotype CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080238

Phase I study of recombinant human CD40 ligand in cancer patients

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Population depletion activates autonomous CD154-dependent survival in biopsylike Burkitt lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Cutting edge: a critical role for CD70 in CD8 T cell priming by CD40-licensed APCs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Mice deficient for the CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Bystander T cell activation--implications for HIV infection and other diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18490492

12 December 2020

Identifiers

DOI

10.1084/JEM.20080238

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

18490492

1 reference