Proto-oncogene FosB: the amino terminus encodes a regulatory function required for transformation (Q36680730)

15 August 2017

Proto-oncogene FosB: the amino terminus encodes a regulatory function required for transformation (English)

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15 August 2017

R Wisdom

1

1 reference

15 August 2017

I M Verma

series ordinal

2

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15 August 2017

language of work or name

English

0 references

publication date

1 May 1993

1 reference

Molecular and Cellular Biology

15 August 2017

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15 August 2017

13

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15 August 2017

5

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15 August 2017

2635-2643

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Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Specific DNA binding of GAL4, a positive regulatory protein of yeast

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

A gene activated by growth factors is related to the oncogene v-jun

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Rapid and efficient site-specific mutagenesis without phenotypic selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

DNA binding activities of three murine Jun proteins: stimulation by Fos.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Fos-associated protein p39 is the product of the jun proto-oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

GAL4 activates gene expression in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

A vector for expressing GAL4(1-147) fusions in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain delta: differences between v- and c-Jun

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Fos and jun cooperate in transcriptional regulation via heterologous activation domains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Trans-dominant negative mutants of Fos and Jun.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Both products of the fosB gene, FosB and its short form, FosB/SF, are transcriptional activators in fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

fosB is a transforming gene encoding a transcriptional activator

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

fos-associated cellular p39 is related to nuclear transcription factor AP-1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Jun and v-jun contain multiple regions that participate in transcriptional activation in an interdependent manner

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Induction of proto-oncogene JUN/AP-1 by serum and TPA.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Identification of a nuclear targeting sequence in the Fos protein

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Constitutive expression of FosB and its short form, FosB/SF, induces malignant cell transformation in rat-1A cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359630

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

5 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/8474434

12 December 2020

Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/8474434

12 December 2020

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8474434

12 December 2020

Structure-function analysis of fos protein: A single amino acid change activates the immortalizing potential of v-fos

1 reference

https://pubmed.ncbi.nlm.nih.gov/8474434

12 December 2020

Identifiers

DOI

10.1128/MCB.13.5.2635

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

8474434

1 reference