Current advances and future challenges in Adenoviral vector biology and targeting (Q36463004)

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1 January 2020

review article

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title

Current advances and future challenges in Adenoviral vector biology and targeting (English)

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1 January 2020

1 reference

1

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1 January 2020

author name string

Michael A Barry

series ordinal

2

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1 January 2020

language of work or name

English

0 references

publication date

1 June 2007

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1 January 2020

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1 January 2020

volume

7

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1 January 2020

issue

3

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1 January 2020

page(s)

189-204

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Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop

1 January 2020

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Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

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Modulation of adenoviral transduction in vitro and in vivo by hyaluronan and its receptor CD44.

30 September 2017

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Adenovirus-induced thrombocytopenia: the role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance

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Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

30 September 2017

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Adenovirus type 5 fiber knob domain has a critical role in fiber protein synthesis and encapsidation

30 September 2017

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A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.

30 September 2017

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Characterization of capsid-modified adenovirus vectors containing heterologous peptides in the fiber knob, protein IX, or hexon

30 September 2017

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Visualization of alpha-helices in a 6-angstrom resolution cryoelectron microscopy structure of adenovirus allows refinement of capsid protein assignments

30 September 2017

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Cryoelectron microscopy of protein IX-modified adenoviruses suggests a new position for the C terminus of protein IX.

30 September 2017

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Role of the putative heparan sulfate glycosaminoglycan-binding site of the adenovirus type 5 fiber shaft on liver detargeting and knob-mediated retargeting

30 September 2017

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Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

30 September 2017

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Improved gene delivery to B lymphocytes using a modified adenovirus vector targeting CD21.

30 September 2017

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Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

30 September 2017

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Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors

30 September 2017

1 reference

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Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.

30 September 2017

1 reference

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Genetic targeting of adenovirus vectors using a reovirus sigma1-based attachment protein

30 September 2017

1 reference

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Dynamic monitoring of oncolytic adenovirus in vivo by genetic capsid labeling

30 September 2017

1 reference

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Transductional targeting of adenovirus vectors for gene therapy

30 September 2017

1 reference

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Generation and selection of targeted adenoviruses embodying optimized vector properties

30 September 2017

1 reference

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Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1.

30 September 2017

1 reference

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CD46 is a cellular receptor for all species B adenoviruses except types 3 and 7.

30 September 2017

1 reference

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Selection of muscle-binding peptides from context-specific peptide-presenting phage libraries for adenoviral vector targeting

30 September 2017

1 reference

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Viral entry, lipid rafts and caveosomes

30 September 2017

1 reference

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An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery

30 September 2017

1 reference

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Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion

30 September 2017

1 reference

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Classification of single-projection reconstructions for cryo-electron microscopy data of icosahedral viruses.

30 September 2017

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Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

30 September 2017

1 reference

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Nuclear targeting of adenovirus type 2 requires CRM1-mediated nuclear export

30 September 2017

1 reference

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Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

30 September 2017

1 reference

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Identification of sites in adenovirus hexon for foreign peptide incorporation

30 September 2017

1 reference

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Helper-dependent adenoviral vectors for gene therapy

30 September 2017

1 reference

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30 September 2017

1 reference

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The innate immune response to adenovirus vectors

30 September 2017

1 reference

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Adenovirus protein VI mediates membrane disruption following capsid disassembly.

30 September 2017

1 reference

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Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs

30 September 2017

1 reference

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Rapid construction of capsid-modified adenoviral vectors through bacteriophage lambda Red recombination.

30 September 2017

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Biology of adenovirus and its use as a vector for gene therapy

30 September 2017

1 reference

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Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses

30 September 2017

1 reference

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Adenovirus protein IX: a new look at an old protein

30 September 2017

1 reference

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Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains.

30 September 2017

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Cytoplasmic dynein mediates adenovirus binding to microtubules

30 September 2017

1 reference

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Fluorescently labeled adenovirus with pIX-EGFP for vector detection

30 September 2017

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Avidin-based targeting and purification of a protein IX-modified, metabolically biotinylated adenoviral vector.

30 September 2017

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Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo

30 September 2017

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A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1.

30 September 2017

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The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3

30 September 2017

1 reference

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How Viruses Enter Animal Cells

30 September 2017

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In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors.

30 September 2017

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Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX

30 September 2017

1 reference

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Cholesterol is required for endocytosis and endosomal escape of adenovirus type 2.

30 September 2017

1 reference

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Adenoviral vectors for gene transfer and therapy

30 September 2017

1 reference

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30 September 2017

Adenovirus endocytosis.

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Development of efficient viral vectors selective for vascular smooth muscle cells

30 September 2017

1 reference

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Sleeping beauty transposition: biology and applications for molecular therapy

30 September 2017

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Integrin alpha3beta1 is an alternative cellular receptor for adenovirus serotype 5

30 September 2017

1 reference

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Association of adenovirus with the microtubule organizing center

30 September 2017

1 reference

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Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge

30 September 2017

1 reference

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Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals

30 September 2017

1 reference

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Genetic content and evolution of adenoviruses

30 September 2017

1 reference

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Genetically targeted adenovirus vector directed to CD40-expressing cells

30 September 2017

1 reference

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General strategy for broadening adenovirus tropism.

30 September 2017

1 reference

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Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture

30 September 2017

1 reference

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Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods

30 September 2017

1 reference

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Adenovirus type 11 uses CD46 as a cellular receptor

30 September 2017

1 reference

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Flexibility of the adenovirus fiber is required for efficient receptor interaction

30 September 2017

1 reference

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Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

30 September 2017

1 reference

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Molecular basis of the inflammatory response to adenovirus vectors

30 September 2017

1 reference

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Adenovirus Interaction with Its Cellular Receptor CAR

30 September 2017

1 reference

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Adenovirus stripping: a versatile method to generate adenovirus vectors with new cell target specificity

30 September 2017

1 reference

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Binding of adenovirus capsid to dipalmitoyl phosphatidylcholine provides a novel pathway for virus entry

30 September 2017

1 reference

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The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses

30 September 2017

1 reference

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The coxsackie B virus and adenovirus receptor resides in a distinct membrane microdomain

30 September 2017

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Antibody-mediated targeting of an adenovirus vector modified to contain a synthetic immunoglobulin g-binding domain in the capsid

30 September 2017

1 reference

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Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape

30 September 2017

1 reference

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Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake

30 September 2017

1 reference

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Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein

30 September 2017

1 reference

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Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX.

30 September 2017

1 reference

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Review: conformation and folding of novel beta-structural elements in viral fiber proteins: the triple beta-spiral and triple beta-helix

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

CAR- or alphav integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Signalling in viral entry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Targeted adenoviral vectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Evolution of adenoviruses as gene therapy vectors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenoviral vectors do not induce, inhibit, or potentiate human platelet aggregation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Artificial extension of the adenovirus fiber shaft inhibits infectivity in coxsackievirus and adenovirus receptor-positive cell lines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Evolution of cell recognition by viruses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Integrin alpha(v)beta1 is an adenovirus coreceptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Structural analysis of a fiber-pseudotyped adenovirus with ocular tropism suggests differential modes of cell receptor interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Rab proteins as membrane organizers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Recombinant adenovirus vectors with knobless fibers for targeted gene transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Dependence of adenovirus infectivity on length of the fiber shaft domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Metabolic biotinylation of recombinant proteins in mammalian cells and in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The first step of adenovirus type 2 disassembly occurs at the cell surface, independently of endocytosis and escape to the cytosol

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

High resolution solution structure of the 1.3S subunit of transcarboxylase from Propionibacterium shermanii

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Dressing up adenoviruses to modify their tropism.. Interview by Florence Paillard

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Structure of adenovirus complexed with its internalization receptor, alphavbeta5 integrin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The subgenus-specific C-terminal region of protein IX is located on the surface of the adenovirus capsid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Geometric control of cell life and death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Organ targeting in vivo using phage display peptide libraries

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Difference imaging of adenovirus: bridging the resolution gap between X-ray crystallography and electron microscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The refined crystal structure of hexon, the major coat protein of adenovirus type 2, at 2.9 A resolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Ion etching of human adenovirus 2: structure of the core.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

30 September 2017

Assembly of adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Molecular composition of the adenovirus type 2 virion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Interactions among the three adenovirus core proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Use of Ar+ plasma etching to localize structural proteins in viruses: studies with adenovirus 2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus polypeptide IX revealed as capsid cement by difference images from electron microscopy and crystallography

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The importance of being acid: the role of acidification in intracellular membrane traffic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Structure and composition of the adenovirus type 2 core

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Chromatin-like organization of the adenovirus chromosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Genetic analysis of adenovirus type 2. VIII. Physical locations of temperature-sensitive mutations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Proline 137 is critical for adenovirus protease encapsidation and activation but not enzyme activity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The structure of the human adenovirus 2 penton

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Structural proteins of adenoviruses. X. Isolation and topography of low molecular weight antigens from the virion of adenovirus type 2.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

The proteinase polypeptide of adenovirus serotype 2 virions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Image reconstruction reveals the complex molecular organization of adenovirus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Preferential activation of Toll-like receptor nine by CD46-utilizing adenoviruses

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Increased transduction of skeletal muscle cells by fibroblast growth factor-modified adenoviral vectors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

A quasi-atomic model of human adenovirus type 5 capsid

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Use of adenovirus protein IX (pIX) to display large polypeptides on the virion--generation of fluorescent virus through the incorporation of pIX-GFP.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

CD46 is a cellular receptor for group B adenoviruses

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Metabolically biotinylated adenovirus for cell targeting, ligand screening, and vector purification

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Non-classical export of an adenovirus structural protein

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Complement activation by recombinant adenoviruses.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Blood clearance rates of adenovirus type 5 in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Type-specific epitope locations revealed by X-ray crystallographic study of adenovirus type 5 hexon

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Gene therapy death prompts review of adenovirus vector

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus-mediated expression of human coagulation factor IX in the rhesus macaque is associated with dose-limiting toxicity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Next-generation adenoviral vectors: new and improved

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Specific binding of the adenovirus capsid to the nuclear envelope

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus core protein V is delivered by the invading virus to the nucleus of the infected cell and later in infection is associated with nucleoli

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Modification of an adenoviral vector with biologically selected peptides: a novel strategy for gene delivery to cells of choice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2244792

Assembly of adenovirus major capsid protein is mediated by a nonvirion protein

4 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Biological and Structural Studies with an Adenovirus Type 2 Temperature-Sensitive Mutant Defective for Uncoating

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Stepwise dismantling of adenovirus 2 during entry into cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Expression of a foreign epitope on the surface of the adenovirus hexon

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Antigens and structure of the adenovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

Structural proteins of adenoviruses. IV. Sequential degradation of the adenovirus type 2 virion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17584037

12 December 2020

10.2174/156652307780859062

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17584037%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17584037%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

17584037

1 reference