Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice (Q36403509)

14 August 2017

Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice (English)

1 reference

14 August 2017

0 references

1 reference

Michael H Kershaw

10

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Phillip K. Darcy

Phillip K Darcy

9

0 references

Nicholas P. Restifo

Nicholas P Restifo

7

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Mark J. Smyth

Mark J Smyth

8

0 references

Liza B John

4

Liza B John

1 reference

14 August 2017

5

Christel Devaud

1 reference

14 August 2017

3

Jennifer A Westwood

1 reference

14 August 2017

2

Hollie J Pegram

1 reference

14 August 2017

1

Sally M Amos

1 reference

14 August 2017

Chris J Clarke

6

1 reference

14 August 2017

16 February 2011

1 reference

Cancer Immunology, Immunotherapy

14 August 2017

1 reference

14 August 2017

60

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14 August 2017

5

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14 August 2017

671-683

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In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I/II study

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Complete regression of advanced primary and metastatic mouse melanomas following combination chemoimmunotherapy.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Programming tumor-reactive effector memory CD8+ T cells in vitro obviates the requirement for in vivo vaccination.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Global changes in gene expression and synergistic interactions induced by TLR9 and TLR3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

RNA recognition and signal transduction by RIG-I-like receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Toll-like receptor and RIG-I-like receptor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Checkpoint blockade in cancer immunotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Toll-like receptors on tumor cells facilitate evasion of immune surveillance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Adoptive-cell-transfer therapy for the treatment of patients with cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Toll-like receptors and innate immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Guidelines for the safe administration of high-dose interleukin-2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Loss of interferon-gamma inducibility of TAP1 and LMP2 in a renal cell carcinoma cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

CpG motifs in bacterial DNA trigger direct B-cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Biologic effects after a single dose of poly(I):poly(C12U) in healthy volunteers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Preferential expression and function of Toll-like receptor 3 in human astrocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499620

Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity.

28 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-011-0984-8

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-011-0984-8

CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-011-0984-8

4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-011-0984-8

CpG-mediated changes in gene expression in murine spleen cells identified by microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-011-0984-8

Expression and regulation of chemokine receptors in human natural killer cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Characterization of the major histocompatibility complex class I deficiencies in B16 melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Intra-tumoral injection of CpG results in the inhibition of tumor growth in murine Colon-26 and B-16 tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Toll-like receptors: linking innate and adaptive immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

A pathway analysis of poly(I:C)-induced global gene expression change in human peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Effects of interferon gamma on native human acute myelogenous leukaemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Local administration of PF-3512676 CpG-B instigates tumor-specific CD8+ T-cell reactivity in melanoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

Upregulation of DF3, in association with ICAM-1 and MHC class II by IFN-gamma in short-term human mammary carcinoma cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/21327636

12 December 2020

10.1007/S00262-011-0984-8

Identifiers

DOI

1 reference

14 August 2017

1 reference

PMC publication ID

3499620

14 August 2017

PubMed publication ID

21327636

1 reference

PMC publication ID

3499620