The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice (Q36367908)

13 August 2017

The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice (English)

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13 August 2017

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H S Jun

1

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13 August 2017

C S Yoon

2

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13 August 2017

L Zbytnuik

3

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13 August 2017

N van Rooijen

4

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13 August 2017

J W Yoon

5

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13 August 2017

language of work or name

English

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publication date

1 January 1999

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Journal of Experimental Medicine

13 August 2017

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13 August 2017

189

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13 August 2017

2

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13 August 2017

347-358

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The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

13 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Beta cell apoptosis in T cell-mediated autoimmune diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Interleukin-12 and its role in the generation of TH1 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Cytokines as mediators of autoimmune diabetes and diabetic complications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Determinants of the selective toxicity of alloxan to the pancreatic B cell

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Antigen-Presenting Function of the Macrophage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

The basis for the immunoregulatory role of macrophages and other accessory cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

The two-signal model of lymphocyte activation twenty-one years later

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Elimination, blocking, and activation of macrophages: three of a kind?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

The role of CD4 and CD8 T cells in type I diabetes in the NOD mouse.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Role of macrophages and macrophage-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes in diabetes-resistant BioBreeding rats

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Transient suppression of macrophage functions by liposome-encapsulated drugs

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Long-term complications of virus-induced diabetes mellitus in mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Effect of vitamin E deficiency and selenium deficiency on insulin secretory reserve and free radical scavenging systems in islets: decrease of islet manganosuperoxide dismutase.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Spontaneous cytotoxicity of macrophages against pancreatic islet cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

T-lymphocyte clone specific for pancreatic islet antigen

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Studies on autoimmunity for initiation of beta-cell destruction. V. Decrease of macrophage-dependent T lymphocytes and natural killer cytotoxicity in silica-treated BB rats.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Studies on Autoimmunity for T-Cell-Mediated β-Cell Destruction: Distinct Difference in β-Cell Destruction Between CD4+ and CD8+ T-Cell Clones Derived From Lymphocytes Infiltrating the Islets of NOD Mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192977

A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique

21 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Dendritic cells and scavenger macrophages in pancreatic islets of prediabetic BB rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Evidence for initial involvement of macrophage in development of insulitis in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Prevention of lymphocytic thyroiditis and insulitis in diabetes-prone BB rats by the depletion of macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. Ultrastructural aspects of elimination of marginal zone macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Administration of silica prevents diabetes in BB-rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Distinct macrophage subpopulations in pancreas of prediabetic BB/E rats. Possible role for macrophages in pathogenesis of IDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Preferential infiltration of macrophages during early stages of insulitis in diabetes-prone BB rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

T helper cell subsets in insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Circulation of human hematopoietic cells in severe combined immunodeficient mice after Cl2MDP-liposome-mediated macrophage depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Prevention of recurrent diabetes in syngenic islet-transplanted NOD mice by transfusion of autoreactive T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Prevention of autoimmune type I diabetes by CD4+ suppressor T cells in superantigen-treated non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

A new type of CD4+ suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Liposome-encapsulated dichloromethylene diphosphonate induces macrophage apoptosis in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

The role of Fas in autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Cellular and molecular mechanisms for the initiation and progression of beta cell destruction resulting from the collaboration between macrophages and T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9892617

12 December 2020

Identifiers

DOI

10.1084/JEM.189.2.347

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

9892617

1 reference