Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse (Q36367533)

13 August 2017

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse (English)

1 reference

13 August 2017

L Gabriele

2

0 references

Klaus Rajewsky

object named as

K Rajewsky

6

0 references

Werner Müller

object named as

W Müller

7

0 references

author name string

R A Morawetz

1

1 reference

13 August 2017

L V Rizzo

3

1 reference

13 August 2017

N Noben-Trauth

4

1 reference

13 August 2017

R Kühn

5

1 reference

13 August 2017

T M Doherty

8

1 reference

13 August 2017

F Finkelman

9

1 reference

13 August 2017

R L Coffman

10

1 reference

13 August 2017

H C Morse

11

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 November 1996

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

184

1 reference

13 August 2017

5

1 reference

13 August 2017

1651-1661

1 reference

Antibody to the ligand for CD40 (gp39) inhibits murine AIDS-associated splenomegaly, hypergammaglobulinemia, and immunodeficiency in disease-susceptible C57BL/6 mice.

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Cells and cytokines in the pathogenesis of MAIDS, a retrovirus-induced immunodeficiency syndrome of mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Towards a comprehensive view of immunoglobulin class switching

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Mechanism and regulation of immunoglobulin isotype switching.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Pentoxifylline and meclofenamic acid treatment reduces clinical manifestations in a murine model of AIDS.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Humoral immune responses in CD40 ligand-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Antibodies of the secondary response can be expressed without switch recombination in normal mouse B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Double isotype production by a neoplastic B cell line. II. Allelically excluded production of mu and gamma 1 heavy chains without CH gene rearrangement

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Retrovirus-induced murine acquired immunodeficiency syndrome: natural history of infection and differing susceptibility of inbred mouse strains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Clonal and molecular characteristics of the human IgE-committed B cell subset

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

IL-4 is required to generate and sustain in vivo IgE responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Establishment of a germ-line competent C57BL/6 embryonic stem cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Regulation of murine in vivo IgG and IgE responses by a monoclonal anti-IL-4 receptor antibody

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

IL-4 requirements for the generation of secondary in vivo IgE responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Molecular and biological characterization of a murine ligand for CD40

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Prostaglandin E2 and cAMP inhibit B lymphocyte activation and simultaneously promote IgE and IgG1 synthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Regulation of the expression of human C epsilon germline transcript. Identification of a novel IL-4 responsive element

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

IFN-gamma represses epsilon germline transcription and subsequently down-regulates switch recombination to epsilon.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Prostaglandin E2 promotes IL-4-induced IgE and IgG1 synthesis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Expression of IgE from a nonrearranged epsilon locus in cloned B-lymphoblastoid cells that also express IgM.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Kinetics of interleukin-4 induction and interferon-γ inhibition of IgE secretion by Epstein-Barr virus-infected human peripheral blood B cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Monoclonal antibodies block murine IL-4 receptor function

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Generation of B cell memory and affinity maturation. Induction with Th1 and Th2 T cell clones

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Regulation of germ-line epsilon transcription and induction of epsilon switching in cloned EBV-transformed and malignant human B cell lines by cytokines and CD4+ T cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

IL-4 induces germ-line IgE heavy chain gene transcription in human fetal pre-B cells. Evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Prostaglandin E2 promotes B lymphocyte Ig isotype switching to IgE

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192860

Characteristics of B cell proliferation and activation in murine AIDS

5 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Germline and productive C epsilon gene expression during in vivo IgE responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Resistance to murine acquired immunodeficiency syndrome (MAIDS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Switch transcripts in immunoglobulin class switching

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

IgD-secreting murine plasmacytomas: identification and partial characterization of two IgD myeloma proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Polyclonal activation of the murine immune system by an antibody to IgD. II. Generation of polyclonal antibody production and cells with surface IgG

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Prostaglandin E2 as a selective stimulator of antigen-specific IgE response in murine lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Generation and analysis of interleukin-4 deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

T helper cell membranes promote IL-4-independent expression of germ-line C gamma 1 transcripts in B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Retrovirus-induced immunodeficiency in the mouse: MAIDS as a model for AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8920855

12 December 2020

Identifiers

DOI

10.1084/JEM.184.5.1651

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

8920855

1 reference