Evolution of antibody structure during the immune response. The differentiative potential of a single B lymphocyte (Q36356890)

13 August 2017

Evolution of antibody structure during the immune response. The differentiative potential of a single B lymphocyte (English)

1 reference

13 August 2017

0 references

1 reference

T Manser

1

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PMC publication ID

2189475

13 August 2017

language of work or name

English

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publication date

1 October 1989

1 reference

Journal of Experimental Medicine

13 August 2017

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13 August 2017

170

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13 August 2017

4

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13 August 2017

1211-1230

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DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatic diversification of immunoglobulins.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Recombination between antibody heavy chain variable-region genes: evidence for gene conversion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Ordered rearrangement of immunoglobulin heavy chain variable region segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

CH Isotype 'Switching' During Normal B-Lymphocyte Development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

The immune response to a simple antigenic determinant

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Cell Selection by Antigen in the Immune Response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Quantitative investigations of idiotypic antibodies. VI. Idiotypic specificity as a potential genetic marker for the variable regions of mouse immunoglobulin polypeptide chains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatically mutated forms of a major anti-p-azophenylarsonate antibody variable region with drastically reduced affinity for p-azophenylarsonate. By-products of an antigen-driven immune response?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Patterns of somatic mutations in immunoglobulin variable genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatic evolution of variable region structures during an immune response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

30 September 2017

Multiplex DNA Sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Evolutionary and somatic selection of the antibody repertoire in the mouse.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatic mutation in anti-phosphorylcholine antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Point mutations cause the somatic diversification of IgM and IgG2a antiphosphorylcholine antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Control of immunoglobulin class switch recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Mutational hot spots in Ig V region genes of human follicular lymphomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p-azophenylarsonate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Gene conversion and the generation of antibody diversity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Influence of the macromolecular form of a B cell epitope on the expression of antibody variable and constant region structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Organization of immunoglobulin heavy chain genes and allelic deletion model

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatic mutation and clonal expansion of B cells in an antigen-driven immune response.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Idiotypic analysis of polyclonal and monoclonal anti-p-azophenylarsonate antibodies of BALB/c mice expressing the major cross-reactive idiotype of the A/J strain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

A limited number of B cell lineages generates the heterogeneity of a secondary immune response.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Sites of switch recombination in IgG2b- and IgG2a-producing hybridomas.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

A hyperconversion mechanism generates the chicken light chain preimmune repertoire

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Molecular limitations on variable-gene junctional diversity.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Idiotypic selection of an antibody mutant with changed hapten binding specificity, resulting from a point mutation in position 50 of the heavy chain.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

29 June 2018

Allergy and Immunology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

The genetic basis of antibody production: a single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Anti-oxazolone hybridomas and the structure of the oxazolone idiotype.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Somatic evolution of diversity among anti-phosphocholine antibodies induced with Proteus morganii

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2189475

Relative combining affinities of anti-p-azophenylarsonate antibodies bearing a cross-reactive idiotype

22 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Molecular events during maturation of the immune response to oxazolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Germ-line sequence of the DH segment employed in Ars-A antibodies: implications for the generation of junctional diversity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

The molecular evolution of the immune response: idiotope-specific suppression indicates that B cells express germ-line-encoded V genes prior to antigenic stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Switch region content of hybridomas: the two spleen cell Igh loci tend to rearrange to the same isotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/2507726

12 December 2020

Identifiers

DOI

10.1084/JEM.170.4.1211

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2w7azzlttjg6hi33izvtfkn2xy

30 July 2022

release_2w7azzlttjg6hi33izvtfkn2xy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2w7azzlttjg6hi33izvtfkn2xy

30 July 2022

https://api.fatcat.wiki/v0/release/2w7azzlttjg6hi33izvtfkn2xy

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/2w7azzlttjg6hi33izvtfkn2xy

PubMed publication ID

1 reference

30 July 2022