On the role of VDAC in apoptosis: fact and fiction (Q36259127)

13 August 2017

title

On the role of VDAC in apoptosis: fact and fiction (English)

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13 August 2017

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Tatiana K Rostovtseva

series ordinal

1

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13 August 2017

Wenzhi Tan

series ordinal

2

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13 August 2017

Marco Colombini

series ordinal

3

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13 August 2017

publication date

1 June 2005

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Journal of Bioenergetics and Biomembranes

13 August 2017

published in

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13 August 2017

volume

37

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13 August 2017

issue

3

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13 August 2017

page(s)

129-142

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Voltage gating in VDAC is markedly inhibited by micromolar quantities of aluminum.

13 August 2017

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Regulation of metabolite flux through voltage-gating of VDAC channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Voltage gating of the mitochondrial outer membrane channel VDAC is regulated by a very conserved protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Molecular genetics of the VDAC ion channel: structural model and sequence analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

A simple method for the determination of the pore radius of ion channels in planar lipid bilayer membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Structure of the outer mitochondrial membrane: ordered arrays of porelike subunits in outer-membrane fractions from neurospora crassa mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Inhibition of adenine nucleotide translocator by lipid peroxidation products

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bid, but not Bax, regulates VDAC channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Inhibition of Bax channel-forming activity by Bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Toward the molecular structure of the mitochondrial channel, VDAC

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The role of pyridine dinucleotides in regulating the permeability of the mitochondrial outer membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Dual mode of gating of voltage-dependent anion channel as revealed by phosphorylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Biphasic translocation of Bax to mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The topology of VDAC as probed by biotin modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Beta-NADH decreases the permeability of the mitochondrial outer membrane to ADP by a factor of 6

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Inhibition of Bax-induced cytochrome c release from neural cell and brain mitochondria by dibucaine and propranolol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Hydrodynamic properties of porin isolated from outer membranes of rat liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bid induces cytochrome c-impermeable Bax channels in liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Reactive oxygen species and the mitochondrial signaling pathway of cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC channels differentiate between natural metabolites and synthetic molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Selectivity Changes in Site-Directed Mutants of the VDAC Ion Channel: Structural Implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The pathophysiology of mitochondrial cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Structural and functional evidence for multiple channel complexes in the outer membrane of Neurospora crassa mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The sensor regions of VDAC are translocated from within the membrane to the surface during the gating processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax-dependent regulation of Bak by voltage-dependent anion channel 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Actin modulates the gating of Neurospora crassa VDAC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Inhibition by aluminum hydroxide of the voltage-dependent closure of the mitochondrial channel, VDAC

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC/porin is present in sarcoplasmic reticulum from skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bcl-2 prevents Bax oligomerization in the mitochondrial outer membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Mitochondrial permeability transitions: how many doors to the house?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Subcellular distribution of rat liver porin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Structure and orientation of two voltage-dependent anion-selective channel isoforms. An attenuated total reflection fourier-transform infrared spectroscopy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC2 inhibits BAK activation and mitochondrial apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Detection of likely transmembrane beta strand regions in sequences of mitochondrial pore proteins using the Gibbs sampler

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The apoptotic protein tBid promotes leakage by altering membrane curvature

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Peptide-specific antibodies and proteases as probes of the transmembrane topology of the bovine heart mitochondrial porin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Dynamics of nucleotides in VDAC channels: structure-specific noise generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Mitochondrial outer membrane permeability change and hypersensitivity to digitonin early in staurosporine-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Lipidic pore formation by the concerted action of proapoptotic BAX and tBID.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

A candidate for the permeability pathway of the outer mitochondrial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Voltage gating in the mitochondrial channel, VDAC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Is there VDAC in cell compartments other than the mitochondria?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Indications of a common folding pattern for VDAC channels from all sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Ca2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms: role of cardiolipin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Ultrasteep voltage dependence in a membrane channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Response of yeast to the regulated expression of proteins in the Bcl-2 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Interaction between the VDAC channel and a polyanionic effector. An electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Mitochondrial permeability transition and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Oxidative stress on mitochondria and cell membrane of cultured rat hepatocytes and perfused liver exposed to ethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Large scale rearrangement of protein domains is associated with voltage gating of the VDAC channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Peptide-specific antibodies as probes of the topography of the voltage-gated channel in the mitochondrial outer membrane of Neurospora crassa

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Surface topography and molecular stoichiometry of the mitochondrial channel, VDAC, in crystalline arrays*1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

One-step on-column affinity refolding purification and functional analysis of recombinant human VDAC1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

A 3D model of the voltage-dependent anion channel (VDAC).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The mitochondrial outer membrane channel, VDAC, is modulated by a soluble protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The mitochondrial permeability transition pore and its role in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

ATP transport through a single mitochondrial channel, VDAC, studied by current fluctuation analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC: the channel at the interface between mitochondria and the cytosol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Investigation of bax-induced release of cytochrome c from yeast mitochondria permeability of mitochondrial membranes, role of VDAC and ATP requirement

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Determination of the number of polypeptide subunits in a functional VDAC channel from Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Hexokinase II: the integration of energy metabolism and control of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Evidence that the crystalline arrays in the outer membrane of Neurospora mitochondria are composed of the voltage-dependent channel protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Ca(2+)-induced mitochondrial membrane permeabilization: role of coenzyme Q redox state

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Characterization and partial purification of the VDAC-channel-modulating protein from calf liver mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

The mitochondrial permeability transition contributes to acute ethanol-induced apoptosis in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

On the structure of mitochondrial porins and its homologies with bacterial porins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16167170

12 December 2020

10.1007/S10863-005-6566-8

Identifiers

DOI

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13 August 2017

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