Human and murine granzyme B exhibit divergent substrate preferences (Q36117776)

12 August 2017

Human and murine granzyme B exhibit divergent substrate preferences (English)

1 reference

12 August 2017

2

Colin Adrain

1 reference

12 August 2017

Seamus J Martin

5

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author name string

Sean P Cullen

series ordinal

1

1 reference

12 August 2017

Alexander U Lüthi

series ordinal

3

1 reference

12 August 2017

Patrick J Duriez

series ordinal

4

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12 August 2017

language of work or name

English

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publication date

5 February 2007

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12 August 2017

10

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

176

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12 August 2017

4

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12 August 2017

435-444

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2063979/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The major human and mouse granzymes are structurally and functionally divergent

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The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

2 October 2017

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Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.

2 October 2017

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Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

2 October 2017

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Granzyme B-mediated apoptosis--the elephant and the blind men?

2 October 2017

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Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response

2 October 2017

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Regulation of the expression and processing of caspase-12

2 October 2017

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The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

2 October 2017

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Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

2 October 2017

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

2 October 2017

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Functional significance of the perforin/granzyme cell death pathway

2 October 2017

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Human caspase 12 has acquired deleterious mutations

2 October 2017

1 reference

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Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

2 October 2017

1 reference

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Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

2 October 2017

1 reference

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

2 October 2017

1 reference

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

2 October 2017

1 reference

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Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

2 October 2017

1 reference

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DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

2 October 2017

1 reference

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

2 October 2017

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CTL granules: evolution of vesicles essential for combating virus infections

2 October 2017

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

2 October 2017

1 reference

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Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

2 October 2017

1 reference

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Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

2 October 2017

1 reference

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

2 October 2017

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

2 October 2017

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

2 October 2017

1 reference

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Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli

2 October 2017

1 reference

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

2 October 2017

1 reference

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The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.

2 October 2017

1 reference

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Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

2 October 2017

1 reference

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

2 October 2017

1 reference

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Granules of cytolytic T-lymphocytes contain two serine esterases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063979

A central role for Bid in granzyme B-induced apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063979

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063979

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063979

Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200612025

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200612025

Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17283187

12 December 2020

inferred from PubMed ID database lookup

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17283187

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200612025

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

17283187

1 reference