Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers. (Q35941288)

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22 February 2020

title

Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers (English)

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22 February 2020

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19

Gabriel N Hortobagyi

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22 February 2020

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Mien-Chie Hung

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22 February 2020

7

Hirohito Yamaguchi

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22 February 2020

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Huang-Chun Lien

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22 February 2020

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Cheng-Chieh Yang

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22 February 2020

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Weiya Xia

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22 February 2020

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Yongkun Wei

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Yi-Hsin Hsu

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22 February 2020

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Jingyu Lang

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Adam LaBaff

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Lei Nie

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Jennifer L Hsu

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Dongping Liu

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Yi Du

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Long-Yuan Li

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Rong Deng

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Li-Chuan Chan

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Jun Yao

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Celina G Kleer

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language of work or name

English

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publication date

15 June 2015

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American Journal of Translational Research

22 February 2020

published in

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volume

7

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22 February 2020

issue

6

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22 February 2020

page(s)

1009-1020

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EZH2 expands breast stem cells through activation of NOTCH1 signaling

22 February 2020

cites work

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NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes

2 October 2017

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Clinical and biological relevance of enhancer of zeste homolog 2 in triple-negative breast cancer

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Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability

2 October 2017

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Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

2 October 2017

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EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling

2 October 2017

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CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

2 October 2017

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Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

2 October 2017

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Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

2 October 2017

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Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2

2 October 2017

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Phosphorylation regulates SIRT1 function.

2 October 2017

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2 October 2017

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Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component

2 October 2017

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The combination of high cyclin E and Skp2 expression in breast cancer is associated with a poor prognosis and the basal phenotype

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response

11 July 2018

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11 July 2018

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24 September 2018

Identifiers

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22 February 2020

PubMed publication ID

26279746

1 reference