Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22. (Q35868577)

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scientific article published in September 1996

Language	Label	Description	Also known as
English	Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.	scientific article published in September 1996

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22. (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

immediate early gene

1 reference

based on heuristic

inferred from title

author name string

N Wu

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

S C Watkins

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

P A Schaffer

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

N A DeLuca

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 September 1996

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

70

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

6358-6369

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes

1 reference

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11 July 2018

Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoter

1 reference

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11 July 2018

Nuclear dot antigens may specify transcriptional domains in the nucleus

1 reference

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11 July 2018

In vitro characterization of a herpes simplex virus type 1 ICP22 deletion mutant

1 reference

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11 July 2018

ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB.

1 reference

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11 July 2018

Repression of the herpes simplex virus 1 alpha 4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sites

1 reference

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11 July 2018

Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region.

1 reference

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11 July 2018

Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

1 reference

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11 July 2018

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1 reference

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11 July 2018

The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency.

1 reference

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11 July 2018

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1 reference

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11 July 2018

Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0

1 reference

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11 July 2018

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion

1 reference

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11 July 2018

Improved cell survival by the reduction of immediate-early gene expression in replication-defective mutants of herpes simplex virus type 1 but not by mutation of the virion host shutoff function.

1 reference

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11 July 2018

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

BICP22 of bovine herpesvirus 1 is encoded by a spliced 1.7 kb RNA which exhibits immediate early and late transcription kinetics

1 reference

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11 July 2018

Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect

1 reference

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11 July 2018

HSV-1 IE protein Vmw110 causes redistribution of PML.

1 reference

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11 July 2018

A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1 genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Properties of an HSV-1 regulatory protein that appears to impair host cell splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Herpes simplex virus immediate-early protein ICP22 is required for viral modification of host RNA polymerase II and establishment of the normal viral transcription program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Evolutionary history of a multigene family: an expressed human beta-tubulin gene and three processed pseudogenes

1 reference

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11 July 2018

Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

1 reference

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11 July 2018

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes.

1 reference

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11 July 2018

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1 reference

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11 July 2018

Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA.

1 reference

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11 July 2018

Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity

1 reference

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11 July 2018

Identification of herpes simplex virus DNA sequences which encode a trans-acting polypeptide responsible for stimulation of immediate early transcription

1 reference

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11 July 2018

Differential Expression of Two Neural Cell-Specific β-Tubulin mRNAs During Rat Brain Development

1 reference

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11 July 2018

Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins

1 reference

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11 July 2018

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides

1 reference

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11 July 2018

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

1 reference

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11 July 2018

A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins

1 reference

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11 July 2018

Chromosome damage induced by herpes simplex virus type 1 in early infection

1 reference

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11 July 2018

Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

1 reference

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11 July 2018

Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation

1 reference

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11 July 2018

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.

1 reference

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11 July 2018

Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene

1 reference

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11 July 2018

Herpes simplex virus type 1 ICP27 is an essential regulatory protein.

1 reference

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11 July 2018

Herpes simplex virus 1 mutant deleted in the alpha 22 gene: growth and gene expression in permissive and restrictive cells and establishment of latency in mice

1 reference

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11 July 2018

Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions

1 reference

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11 July 2018

Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1.

1 reference

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11 July 2018

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1 reference

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11 July 2018

Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression

1 reference

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11 July 2018

The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein

1 reference

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11 July 2018

Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1 reference

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11 July 2018

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins

1 reference

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11 July 2018

The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

1 reference

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11 July 2018

Herpes simplex virus Vmw65-octamer binding protein interaction: a paradigm for combinatorial control of transcription

1 reference

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11 July 2018

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein

1 reference

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11 July 2018

Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation

1 reference

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11 July 2018

Separation of requirements for protein-DNA complex assembly from those for functional activity in the herpes simplex virus regulatory protein Vmw65.

1 reference

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11 July 2018

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency

1 reference

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11 July 2018

Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Identification of a novel nuclear domain

1 reference

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11 July 2018

Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene

1 reference

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11 July 2018

Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27.

1 reference

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11 July 2018

Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1

1 reference

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11 July 2018

ICP22 homolog of equine herpesvirus 1: expression from early and late promoters

1 reference

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11 July 2018

Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing

1 reference

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11 July 2018

A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing

1 reference

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11 July 2018

Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells

1 reference

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11 July 2018

Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 reference

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11 July 2018

Separation and characterization of herpes simplex virus type 1 immediate-early mRNA's

1 reference

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11 July 2018

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1 reference

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11 July 2018

Characterization of transcription-deficient temperature-sensitive mutants of herpes simplex virus type 1

1 reference

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11 July 2018

Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome

1 reference

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11 July 2018

Regulation of herpesvirus macromolecular synthesis V. Properties of α polypeptides made in HSV-1 and HSV-2 infected cells

1 reference

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11 July 2018

Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

11 July 2018

The nuclear location of PML, a cellular member of the C3HC4 zinc-binding domain protein family, is rearranged during herpes simplex virus infection by the C3HC4 viral protein ICP0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

24 September 2018

Herpes simplex virus induces a processing factor that stimulates poly(A) site usage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=190662

24 September 2018

Transcription of herpes simplex type 1 DNA in nuclei isolated from infected HEp-2 and KB cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8709264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment

1 reference

https://pubmed.ncbi.nlm.nih.gov/8709264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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