Inflammatory resolution: new opportunities for drug discovery (Q35770168)

10 August 2017

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title

Inflammatory resolution: new opportunities for drug discovery (English)

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10 August 2017

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Derek W Gilroy

1

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Mauro Perretti

series ordinal

3

object named as

Mauro Perretti

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10 August 2017

Toby Lawrence

2

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10 August 2017

Adriano G Rossi

series ordinal

4

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10 August 2017

publication date

1 May 2004

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Nature Reviews Drug Discovery

10 August 2017

published in

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10 August 2017

volume

3

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10 August 2017

issue

5

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10 August 2017

page(s)

401-416

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The reaction of guinea-pigs to autologous and heterologous fibrin implants

10 August 2017

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31 March 2020

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Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation

31 March 2020

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Inducible cyclooxygenase may have anti-inflammatory properties

31 March 2020

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A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation

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31 March 2020

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The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.

31 March 2020

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The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.

31 March 2020

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15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Lipid mediator class switching during acute inflammation: signals in resolution.

31 March 2020

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Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction

31 March 2020

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Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor

31 March 2020

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Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes.

31 March 2020

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Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia

31 March 2020

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Cutting Edge: Lipoxins Rapidly Stimulate Nonphlogistic Phagocytosis of Apoptotic Neutrophils by Monocyte-Derived Macrophages

31 March 2020

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31 March 2020

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31 March 2020

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Cutting Edge: Lipoxin (LX) A4 and Aspirin-Triggered 15-Epi-LXA4 Block Allergen-Induced Eosinophil Trafficking

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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

31 March 2020

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Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

31 March 2020

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Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases

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31 March 2020

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Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).

31 March 2020

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Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis.

31 March 2020

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15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure

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An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile

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Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis

31 March 2020

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Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence

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Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation

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Corpse clearance defines the meaning of cell death

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From bench to clinic with apoptosis-based therapeutic agents

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31 March 2020

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A blast from the past: clearance of apoptotic cells regulates immune responses.

31 March 2020

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Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets.

31 March 2020

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An appetite for apoptotic cells? Controversies and challenges

31 March 2020

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Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac.

31 March 2020

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Eosinophil apoptosis and the resolution of airway inflammation in asthma

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Therapeutic approaches to the modulation of apoptosis

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31 March 2020

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Caspase inhibitors as anti-inflammatory and antiapoptotic agents.

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The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials

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The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injury

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First clinical trial of a novel caspase inhibitor: anti-apoptotic caspase inhibitor, IDN-6556, improves liver enzymes.

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New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

31 March 2020

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NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

31 March 2020

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Possible new role for NF-kappaB in the resolution of inflammation.

31 March 2020

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Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50.

31 March 2020

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Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.

31 March 2020

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The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

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Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

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A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats

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The effect of adrenalectomy on interleukin-1 release in vitro and in vivo

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Molecular mechanisms of glucocorticosteroid actions.

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Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

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Bioenergetics of immune functions: fundamental and therapeutic aspects

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

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Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids

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Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line

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Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids

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Annexins: from structure to function

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Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

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Formyl-peptide receptors revisited

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Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1.

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Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse

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Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.

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The annexin 1 receptor(s): is the plot unravelling?

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Adenosine: an endogenous regulator of innate immunity

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Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo

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31 March 2020

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Adenosine: a potential mediator of immunosuppression in multiple organ failure

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Targeting melanocortin receptors as a novel strategy to control inflammation.

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The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

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Annexin I Is an Endogenous Ligand that Mediates Apoptotic Cell Engulfment

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRD1383

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet-granulocyte suspensions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD1383

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRD1383

1 reference

10 August 2017

1 reference