Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis (Q35674584)

9 August 2017

title

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis (English)

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9 August 2017

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Bin Zhao

1

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9 August 2017

Li Li

2

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9 August 2017

Lloyd Wang

3

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9 August 2017

Cun-Yu Wang

4

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9 August 2017

Jindan Yu

5

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9 August 2017

Kun-Liang Guan

6

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9 August 2017

publication date

1 January 2012

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9 August 2017

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9 August 2017

volume

26

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9 August 2017

issue

1

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9 August 2017

page(s)

54-68

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Hippo pathway regulation by cell morphology and stress fibers.

9 August 2017

cites work

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E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.

12 July 2018

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Role of YAP/TAZ in mechanotransduction

12 July 2018

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α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1

12 July 2018

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Modulating F-actin organization induces organ growth by affecting the Hippo pathway

12 July 2018

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Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila

12 July 2018

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Yap1 acts downstream of α-catenin to control epidermal proliferation

12 July 2018

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Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

12 July 2018

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Hippo pathway-independent restriction of TAZ and YAP by angiomotin

12 July 2018

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Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

12 July 2018

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Angiomotin-like proteins associate with and negatively regulate YAP1

12 July 2018

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Hippo signaling: growth control and beyond

12 July 2018

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The extracellular matrix at a glance

12 July 2018

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The Hippo Signaling Pathway in Development and Cancer

12 July 2018

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The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.

12 July 2018

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Cell adhesion: integrating cytoskeletal dynamics and cellular tension

12 July 2018

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

12 July 2018

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Integrative genomic profiling of human prostate cancer

12 July 2018

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

12 July 2018

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

12 July 2018

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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

12 July 2018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

12 July 2018

1 reference

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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

12 July 2018

1 reference

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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

12 July 2018

1 reference

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Cytoskeletal control of growth and cell fate switching

12 July 2018

1 reference

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Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

12 July 2018

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The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

12 July 2018

1 reference

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Anoikis: a necessary death program for anchorage-dependent cells

12 July 2018

1 reference

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Expression of Yes-associated protein in common solid tumors

12 July 2018

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TEAD mediates YAP-dependent gene induction and growth control

12 July 2018

1 reference

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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

12 July 2018

1 reference

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MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

12 July 2018

1 reference

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TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

12 July 2018

1 reference

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Tumor suppressor LATS1 is a negative regulator of oncogene YAP

12 July 2018

1 reference

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

Elucidation of a universal size-control mechanism in Drosophila and mammals

12 July 2018

1 reference

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

12 July 2018

1 reference

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

12 July 2018

1 reference

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

12 July 2018

1 reference

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Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

12 July 2018

1 reference

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The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

12 July 2018

The Hallmarks of Cancer

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Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase

12 July 2018

1 reference

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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258966

Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22215811

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.173435.111

1 reference

9 August 2017

1 reference

9 August 2017

1 reference