CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I-mediated DNA damage. (Q35651126)

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31 October 2019

title

CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I-mediated DNA damage (English)

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31 October 2019

0 references

1

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31 October 2019

author name string

P Fiorani

series ordinal

2

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31 October 2019

M Sugawara

series ordinal

3

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31 October 2019

M A Bjornsti

series ordinal

4

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31 October 2019

language of work or name

English

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publication date

1 September 1999

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Proceedings of the National Academy of Sciences of the United States of America

31 October 2019

published in

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31 October 2019

volume

96

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31 October 2019

issue

20

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page(s)

11440-11445

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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

31 October 2019

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Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.

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Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication

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Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

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The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

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CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication

27 July 2018

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Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

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Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit

27 July 2018

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Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

27 July 2018

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CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication

27 July 2018

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Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA.

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Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

27 July 2018

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SV40 DNA replication intermediates: analysis of drugs which target mammalian DNA replication

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SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I

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DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae

21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/10500195

12 December 2020

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

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12 December 2020

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

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12 December 2020

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

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12 December 2020

Identifiers

DOI

10.1073/PNAS.96.20.11440

1 reference

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31 October 2019

0 references

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31 October 2019

PubMed publication ID

10500195

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